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1. WO1996005229 - HUMAN-MURINE CHIMERIC ANTIBODIES AGAINST RESPIRATORY SYNCYTIAL VIRUS

Publication Number WO/1996/005229
Publication Date 22.02.1996
International Application No. PCT/US1995/010053
International Filing Date 09.08.1995
Chapter 2 Demand Filed 14.02.1996
IPC
A61K 38/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
C07K 16/10 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
08against material from viruses
10from RNA viruses
CPC
A61K 2039/505
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
505comprising antibodies
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
A61P 11/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
C07K 16/1027
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
08against material from viruses
10from RNA viruses ; , e.g. hepatitis E virus
1027Paramyxoviridae, e.g. respiratory syncytial virus
C07K 2317/24
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
2317Immunoglobulins specific features
20characterized by taxonomic origin
24containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
C07K 2317/30
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
2317Immunoglobulins specific features
30characterized by aspects of specificity or valency
Applicants
  • MEDIMMUNE, INC. [US/US]; 35 West Watkins Mill Road Gaithersburg, MD 20878, US
Inventors
  • JOHNSON, Leslie, Sid; US
Agents
  • FERRARO, Gregory, D. ; Carella, Byrne, Bain, Gilfillan, Cecchi, Stewart & Olstein 6 Becker Farm Road Roseland, NJ 07068, US
Priority Data
08/290,59215.08.1994US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) HUMAN-MURINE CHIMERIC ANTIBODIES AGAINST RESPIRATORY SYNCYTIAL VIRUS
(FR) ANTICORPS CHIMERIQUES HUMAINS-MURINS OPPOSES AU VIRUS RESPIRATOIRE SYNCYTIAL
Abstract
(EN)
This invention relates to a human antibody which contains the one CDR from each variable heavy and variable light chain of at least one muring monoclonal antibody, against respiratory syncytial virus which is MAb1129 and the use thereof for the prevention and/or treatment of RSV infection.
(FR)
L'invention concerne un anticorps humain, qui contient la CDR (région déterminante de complémentarité) de chaque chaîne variable, lourde ou légère, d'un anticorps monoclonal murin au moins, MAb1129, qui s'oppose au virus respiratoire syncytial (RSV), et elle concerne son utilisation pour prévenir et/ou traiter une infection à RSV.
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