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1. WO1996005221 - CALCITONIN RECEPTOR

Publication Number WO/1996/005221
Publication Date 22.02.1996
International Application No. PCT/US1994/009235
International Filing Date 16.08.1994
Chapter 2 Demand Filed 28.02.1996
IPC
A61K 38/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
C07K 14/72 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
705Receptors; Cell surface antigens; Cell surface determinants
72for hormones
CPC
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
A61P 1/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
04for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
A61P 11/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
A61P 13/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
13Drugs for disorders of the urinary system
02of urine or of the urinary tract, e.g. urine acidifiers
A61P 15/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
15Drugs for genital or sexual disorders
C07K 14/72
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
705Receptors; Cell surface antigens; Cell surface determinants
72for hormones
Applicants
  • HUMAN GENOME SCIENCES, INC. [US/US]; Suite 300 9620 Medical Center Drive Rockville, MD 20850-3338, US (AllExceptUS)
  • LI, Yi [CN/US]; US (UsOnly)
  • LEE, Norman, H. [US/US]; US (UsOnly)
Inventors
  • LI, Yi; US
  • LEE, Norman, H.; US
Agents
  • OLSTEIN, Elliot, M., ; Carella, Byrne, Bain, Gilfillan, Cecchi, Stewart & Olstein 6 Becker Farm Road Roseland, NJ 07068, US
Priority Data
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) CALCITONIN RECEPTOR
(FR) RECEPTEUR DE CALCITONINE
Abstract
(EN)
A human calcitonin receptor polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide for identifying antagonists and agonists to such polypeptide. Antagonists against such polypeptides may be used therapeutically to treat hypocalcemia and agonists which may be used to treat hypercalcemia and disorders of bone remodelling.
(FR)
Polypeptide récepteur de calcitonine humaine et ADN (ARN) codant ce polypeptide et procédé de production de ce polypeptide par une technique de recombinaison. On décrit également des procédés d'utilisation de ce polypeptide pour l'identification d'antagonistes et d'agonistes de ce polypeptide. On peut utiliser en thérapie lesdits antagonistes pour traiter l'hypocalcémie, et les agonistes pour traiter l'hypercalcémie et les troubles de remodelage osseux.
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