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1. WO1996005195 - NOVEL N-SUBSTITUTED NAPHTHOFUSED LACTAMS

Publication Number WO/1996/005195
Publication Date 22.02.1996
International Application No. PCT/DK1995/000332
International Filing Date 17.08.1995
Chapter 2 Demand Filed 13.03.1996
IPC
C07D 223/14 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
223Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
14condensed with carbocyclic rings or ring systems
C07D 403/10 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
403Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/167
02containing two hetero rings
10linked by a carbon chain containing aromatic rings
C07D 413/14 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
413Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
14containing three or more hetero rings
CPC
C07D 223/14
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
223Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
14condensed with carbocyclic rings or ring systems
C07D 403/10
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
403Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
02containing two hetero rings
10linked by a carbon chain containing aromatic rings
C07D 413/14
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
413Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
14containing three or more hetero rings
Applicants
  • NOVO NORDISK A/S [DK/DK]; Novo Allé DK-2880 Bagsværd, DK (AllExceptUS)
  • THØGERSEN, Henning [DK/DK]; DK (UsOnly)
  • HANSEN, Birgit, Sehested [DK/DK]; DK (UsOnly)
  • PESCHKE, Bernd [DK/DK]; DK (UsOnly)
  • HANSEN, Thomas, Kruse [DK/DK]; DK (UsOnly)
  • ANDERSEN, Knud, Erik [DK/DK]; DK (UsOnly)
Inventors
  • THØGERSEN, Henning; DK
  • HANSEN, Birgit, Sehested; DK
  • PESCHKE, Bernd; DK
  • HANSEN, Thomas, Kruse; DK
  • ANDERSEN, Knud, Erik; DK
Common Representative
  • NOVO NORDISK A/S; att.: Marianne Larsen Corporate Patents Novo Allé DK-2880 Bagsvaerd, DK
Priority Data
0952/9417.08.1994DK
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) NOVEL N-SUBSTITUTED NAPHTHOFUSED LACTAMS
(FR) NOUVEAUX LACTAMES NAPHTOFUSIONNES A SUBSTITUTION N
Abstract
(EN)
Disclosed are novel N-substituted naphthofused lactams and salts thereof of formula (I). Compounds of general formula (I) possess the ability to stimulate the release of endogenous growth hormone. Thus, these compounds may be used in the treatment of conditions which require stimulation of growth hormone production or secretion such as in humans with growth hormone deficiency or where increased growth hormone plasma levels are desired, for instance in elderly patients or in livestock.
(FR)
L'invention concerne de nouveaux lactames naphtofusionnés à substitution N ainsi que leurs sels de formule (I). Les composés de formule (I) présentent la capacité de stimuler la libération de l'hormone de croissance endogène. Ainsi, on peut utiliser ces composés dans le traitement d'états nécessitant une stimulation de la production ou de la sécrétion de l'hormone de croissance tels que chez des individus présentant une carence en hormone de croissance ou lorsque l'on veut augmenter les niveaux d'hormone de croissance dans le plasma, par exemple chez des patients agés ou chez des animaux d'élevage.
Also published as
CZPV1997-458
NO19970684
US08790133
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