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1. WO1996005189 - INHIBITORS OF THE BENZAMIDINE TYPE

Publication Number WO/1996/005189
Publication Date 22.02.1996
International Application No. PCT/CH1995/000174
International Filing Date 09.08.1995
Chapter 2 Demand Filed 19.02.1996
IPC
C07D 295/26 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
295Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
22with hetero atoms directly attached to ring nitrogen atoms
26Sulfur atoms
C12Q 1/56 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
56involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
CPC
C07D 295/26
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
295Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2.] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
22with hetero atoms directly attached to ring nitrogen atoms
26Sulfur atoms
C12Q 1/56
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
56involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
G01N 2333/974
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
2333Assays involving biological materials from specific organisms or of a specific nature
90Enzymes; Proenzymes
914Hydrolases (3)
948acting on peptide bonds (3.4)
974Thrombin
Applicants
  • PENTAPHARM AG [CH/CH]; Engelgasse 109 CH-4052 Basel, CH (AllExceptUS)
  • STÜRZEBECHER, Jörg [DE/DE]; DE (UsOnly)
  • VIEWEG, Helmut [DE/DE]; DE (UsOnly)
  • WIKSTROEM, Peter [SE/CH]; CH (UsOnly)
Inventors
  • STÜRZEBECHER, Jörg; DE
  • VIEWEG, Helmut; DE
  • WIKSTROEM, Peter; CH
Agents
  • BRAUN, André; Murtengasse 5 CH-4051 Basel, CH
Priority Data
2469/94-909.08.1994CH
Publication Language German (DE)
Filing Language German (DE)
Designated States
Title
(DE) NEUE INHIBITOREN VOM BENZAMIDINTYP
(EN) INHIBITORS OF THE BENZAMIDINE TYPE
(FR) NOUVEAUX INHIBITEURS DE TYPE BENZAMIDINE
Abstract
(DE)
Es wurden neue Thrombininhibitoren vom Amidinophenylalanin-Typ gefunden. Die Verbindungen sind insbesondere auch oral und rektal resorbierbar.
(EN)
Disclosed are thrombin inhibitors of the amidinophenylalanine type. The compounds are particular suitable for oral and rectal resorption.
(FR)
L'invention concerne de nouveaux inhibiteurs de thrombine de type amidinophénylalanine. Les composés sont résorbables notamment par voie rectale et par voie orale.
Also published as
Latest bibliographic data on file with the International Bureau