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1. WO1996004927 - NOVEL GnRH ANALOGUES WITH ANTITUMOUR EFFECTS AND PHARMACEUTICAL COMPOSITIONS THEREOF

Publication Number WO/1996/004927
Publication Date 22.02.1996
International Application No. PCT/US1995/010054
International Filing Date 09.08.1995
IPC
A61K 38/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
C07K 7/23 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
7Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04Linear peptides containing only normal peptide links
23Luteinising hormone-releasing hormone (LHRH); Related peptides
CPC
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
C07K 7/23
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
7Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04Linear peptides containing only normal peptide links
23Luteinising hormone-releasing hormone [LHRH]; Related peptides
Applicants
  • LOVAS, Sandor [HU/US]; US
  • MURPHY, Richard, F. [IE/US]; US
  • TOTH, Geza [HU/HU]; HU
  • KALNAY, Adrienn [HU/HU]; HU
  • GAAL, Dezso [HU/HU]; HU
  • PALYI, Istvan [HU/HU]; HU
  • TURI, Gizella [HU/HU]; HU
  • VINCZE, Borbala [HU/HU]; HU
  • MEZO, Imre [HU/HU]; HU
  • TANAI, Henrietta [HU/HU]; HU
  • VADASZ, Zsott [HU/HU]; HU
  • TEPLAN, Istvan [HU/HU]; HU
  • SEPRODI, Janos [HU/HU]; HU
  • SZABÓ, Edit, Z.; HU (UsOnly)
  • PATÓ, János, P.; HU (UsOnly)
  • MÓRA, Melinda; HU (UsOnly)
Inventors
  • LOVAS, Sandor; US
  • MURPHY, Richard, F.; US
  • TOTH, Geza; HU
  • KALNAY, Adrienn; HU
  • GAAL, Dezso; HU
  • PALYI, Istvan; HU
  • TURI, Gizella; HU
  • VINCZE, Borbala; HU
  • MEZO, Imre; HU
  • TANAI, Henrietta; HU
  • VADASZ, Zsott; HU
  • TEPLAN, Istvan; HU
  • SEPRODI, Janos; HU
  • SZABÓ, Edit, Z.; HU
  • PATÓ, János, P.; HU
  • MÓRA, Melinda; HU
Agents
  • ADLER, Benjamin, A.; 8011 Candle Lane Houston, TX 77071, US
Priority Data
P 94 0232810.08.1994HU
P 94 0232910.08.1994HU
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) NOVEL GnRH ANALOGUES WITH ANTITUMOUR EFFECTS AND PHARMACEUTICAL COMPOSITIONS THEREOF
(FR) NOUVEAUX ANALOGUES DE GnRH A EFFETS ANTITUMORAUX ET COMPOSITIONS PHARMACEUTIQUES LES CONTENANT
Abstract
(EN)
The present invention provides pharmacologically active compounds of formula (I). The compounds are GnRH analogues according to the instant invention formulas. Furthermore the invention provides pharmaceutical compositions with the compounds according to the invention as their active ingredients wherein the compositions have an antitumor effect.
(FR)
L'invention concerne des composés pharmacologiquement actifs de formule (I) qui constituent des analogues de GnRH (gonadolibérine). Elle concerne aussi des compositions pharmaceutiques, contenant ces composés en tant qu'ingrédients actifs, qui présentent un effet antitumoral.
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