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Machine translation
1. (WO1996004920) INTERLEUKIN-5 PRODUCTION INHIBITOR
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1996/004920    International Application No.:    PCT/JP1995/001592
Publication Date: 22.02.1996 International Filing Date: 10.08.1995
Chapter 2 Demand Filed:    11.03.1996    
IPC:
C07H 17/08 (2006.01)
Applicants: TAISHO PHARMACEUTICAL CO., LTD. [JP/JP]; 24-1, Takata 3-chome, Toshima-ku, Tokyo 171 (JP) (For All Designated States Except US).
HOSHINO, Akihiko [JP/JP]; (JP) (For US Only).
KASHIMURA, Masato [JP/JP]; (JP) (For US Only).
ASAKA, Toshifumi [JP/JP]; (JP) (For US Only).
INOUE, Tomoyuki [JP/JP]; (JP) (For US Only).
OKUDAIRA, Hirokazu [JP/JP]; (JP) (For US Only)
Inventors: HOSHINO, Akihiko; (JP).
KASHIMURA, Masato; (JP).
ASAKA, Toshifumi; (JP).
INOUE, Tomoyuki; (JP).
OKUDAIRA, Hirokazu; (JP)
Agent: KITAGAWA, Tomizo; Taisho Pharmaceutical Co., Ltd., Patent Division, 24-1, Takata 3-chome, Toshima-ku, Tokyo 171 (JP)
Priority Data:
6/190289 12.08.1994 JP
6/190292 12.08.1994 JP
Title (EN) INTERLEUKIN-5 PRODUCTION INHIBITOR
(FR) INHIBITEUR DE PRODUCTION DE L'INTERLEUKINE-5
Abstract: front page image
(EN)Object: to provide an erythromycin derivative having a potent interleukin-5 production inhibitory effect. Constitution: an interleukin-5 production inhibitor containing as the active ingredient an erythromycin derivative, such as 6-O-methylerythromycin A 9-[O-(2-chlorophenylmethyl)oxime], 6-O-methylerythromycin A 9-[O-(3-methoxy-4-t-butylbenzyl)oxime] 11,12-cyclic carbonate or 11-amino-9-N, 11-N-cyclic ethylene-9-deoxo-11-deoxy-6-O-methylerythromycin A 9-benzylamine 11-N, 12-O-cyclic carbamate, or a medicinally acceptable acid-addition salt thereof.
(FR)Un dérivé de l'érythromycine présente un puissant effet inhibiteur de la production d'interleukine-5. Ce dérivé d'érythromycine, ingrédient actif de l'inhibiteur de production d'interleukine-5, peut être 6-O-méthylérythromycine A 9-[O-(2-chlorophénylméthyl)oxyme], carbonate de 6-O-méthylérythromycine A 9-[O-(3-méthoxy-4-t-butylbenzyl)oxyme] 11,12-cyclique ou 11-amino-9-N, 11-N-cyclique éthylène-9-déoxo-11-déoxy-6-O-méthylérythromycine A 9-benzylamine 11-N, carbamate 12-O-cyclique, ou l'un de leurs sels d'addition d'acide médicalement acceptable.
Designated States: AU, CA, CN, KR, US.
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)