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1. WO1996004916 - METHODS AND COMPOSITIONS USEFUL IN PROPHYLAXIS AND THERAPY OF ENDOTOXIN RELATED CONDITIONS

Publication Number WO/1996/004916
Publication Date 22.02.1996
International Application No. PCT/US1995/010189
International Filing Date 10.08.1995
Chapter 2 Demand Filed 07.03.1996
IPC
A61K 9/127 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
10Dispersions; Emulsions
127Liposomes
CPC
A61K 31/685
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
66Phosphorus compounds
683Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
685one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
A61K 9/1275
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
10Dispersions; Emulsions
127Liposomes
1275Lipoproteins; Chylomicrons; Artificial HDL, LDL, VLDL, protein-free species thereof; Precursors thereof
A61P 1/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
C07K 14/775
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
775Apolipopeptides
Applicants
  • THE ROGOSIN INSTITUTE [US/US]; 505 East 70th Street New York, NY 10021, US (AllExceptUS)
  • LEVINE, Daniel, M. [US/US]; US (UsOnly)
  • PARKER, Thomas, S. [US/US]; US (UsOnly)
  • RUBIN, Albert, L. [US/US]; US (UsOnly)
  • GORDON, Bruce, R. [US/US]; US (UsOnly)
  • SAAL, Stuart, D. [US/US]; US (UsOnly)
Inventors
  • LEVINE, Daniel, M.; US
  • PARKER, Thomas, S.; US
  • RUBIN, Albert, L.; US
  • GORDON, Bruce, R.; US
  • SAAL, Stuart, D.; US
Agents
  • HANSON, Norman, D.; Felfe & Lynch 805 Third Avenue New York, NY 10022, US
Priority Data
08/288,56810.08.1994US
08/487,45907.06.1995US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHODS AND COMPOSITIONS USEFUL IN PROPHYLAXIS AND THERAPY OF ENDOTOXIN RELATED CONDITIONS
(FR) PROCEDE ET COMPOSITIONS UTILES DANS LA PROPHYLAXIE ET LA THERAPIE D'ETATS LIES A L'ENDOTOXINE
Abstract
(EN)
Treatment and prophylaxis of endotoxin caused toxicity is disclosed. This is accomplished by administering phospholipid containing compositions to the subject. The compositions are protein and peptide free, and may contain triglycerides, other polar or neutral lipids, bile acids, or bile acid salts.
(FR)
L'invention concerne le traitement et la prophylaxie de la toxicité induite par l'endotoxine. Ce traitement consiste à administrer au sujet des compositions contenant du phospholipide. Les compositions sont dépourvues de protéine et de peptide, et peuvent contenir des triglycérides, d'autres lipides polaires ou neutres, des acides biliaires, ou des sels d'acides biliaires.
Also published as
CZPV1997-371
FI970534
NO19970582
NZ292315
RO97-00266
SK17697
SK199700176
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