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1. WO1996004904 - PHARMACEUTICALLY STABLE OXALIPLATINUM PREPARATION

Publication Number WO/1996/004904
Publication Date 22.02.1996
International Application No. PCT/IB1995/000614
International Filing Date 07.08.1995
Chapter 2 Demand Filed 25.01.1996
IPC
A61K 31/282 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
28Compounds containing heavy metals
282Platinum compounds
A61K 33/24 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
33Medicinal preparations containing inorganic active ingredients
24Heavy metals; Compounds thereof
CPC
A61K 31/282
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
28Compounds containing heavy metals
282Platinum compounds
A61K 33/24
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
33Medicinal preparations containing inorganic active ingredients
24Heavy metals; Compounds thereof
Applicants
  • DEBIOPHARM S.A. [CH/CH]; 17, rue des Terreaux Case postale 82 CH-1000 Lausanne 9, CH (AllExceptUS)
  • IBRAHIM, Houssam [CH/CH]; CH (UsOnly)
  • MAUVERNAY, Rolland-Yves [FR/CH]; CH (UsOnly)
Inventors
  • IBRAHIM, Houssam; CH
  • MAUVERNAY, Rolland-Yves; CH
Agents
  • MICHELI & CIE; 122, rue de Genève Case postale 61 CH-1226 Thônex, CH
Priority Data
2462/94-608.08.1994CH
Publication Language French (FR)
Filing Language French (FR)
Designated States
Title
(EN) PHARMACEUTICALLY STABLE OXALIPLATINUM PREPARATION
(FR) PREPARATION PHARMACEUTIQUEMENT STABLE D'OXALIPLATINE
Abstract
(EN)
A pharmaceutically stable oxaliplatinum preparation for parenteral administration comprises an aqueous solution of oxaliplatinum, in a concentration of 1 to 5 mg/ml, and with a pH in the range of 4.5 to 6. The aqueous oxaliplatinum solution is advantageously provided as a ready-to-use preparation in a sealed container.
(FR)
Cette invention concerne une préparation pharmaceutiquement stable d'oxaliplatine pour administration par voie parentérale, qui est constituée par une solution d'oxaliplatine dans l'eau en une concentration de 1 à 5 mg/ml, dont le pH est de 4,5 à 6. Cette solution aqueuse d'oxaliplatine se présente avantageusement sous la forme d'une préparation prête à l'emploi qui est contenue dans un récipient fermé hermétiquement.
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