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1. WO1996004558 - MEASUREMENT SYSTEM USING WHOLE BLOOD

Publication Number WO/1996/004558
Publication Date 15.02.1996
International Application No. PCT/JP1995/001510
International Filing Date 28.07.1995
IPC
G01N 33/543 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
543with an insoluble carrier for immobilising immunochemicals
G01N 33/569 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
569for microorganisms, e.g. protozoa, bacteria, viruses
CPC
G01N 2333/02
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
2333Assays involving biological materials from specific organisms or of a specific nature
005from viruses
01DNA viruses
02Hepadnaviridae, e.g. hepatitis B virus
G01N 33/54306
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
543with an insoluble carrier for immobilising immunochemicals
54306Solid-phase reaction mechanisms
G01N 33/569
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
569for microorganisms, e.g. protozoa, bacteria, viruses
G01N 33/56983
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
569for microorganisms, e.g. protozoa, bacteria, viruses
56983Viruses
Y10S 436/82
YSECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
10TECHNICAL SUBJECTS COVERED BY FORMER USPC
STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
436Chemistry: analytical and immunological testing
82Hepatitis associated antigens and antibodies
Applicants
  • IATRON LABORATORIES, INC. [JP/JP]; 11-4, Higashi-kanda 1-chome Chiyoda-ku Tokyo 101, JP (AllExceptUS)
  • HOSHINO, Nobuhiro [JP/JP]; JP (UsOnly)
  • KAWAMOTO, Michiko [JP/JP]; JP (UsOnly)
  • SHIMAMOTO, Mitoshi [JP/JP]; JP (UsOnly)
Inventors
  • HOSHINO, Nobuhiro; JP
  • KAWAMOTO, Michiko; JP
  • SHIMAMOTO, Mitoshi; JP
Agents
  • MORITA, Kenichi; 5th Floor, Itabashi-chuo Building 67-8, Itabashi 2-chome Itabashi-ku Tokyo 173, JP
Priority Data
6/19720729.07.1994JP
Publication Language Japanese (JA)
Filing Language Japanese (JA)
Designated States
Title
(EN) MEASUREMENT SYSTEM USING WHOLE BLOOD
(FR) SYSTEME DE MESURE FONCTIONNANT AVEC DU SANG ENTIER
Abstract
(EN)
An adequate amount of whole blood sample is kept in contact with an insoluble carrier covered with a first partner specifically bindable to a measurement object for short period of time. After the combination of the object with the first partner on the insoluble carrier is brought into contact with a second partner by specific binding to the object, the resulting complex comprising the insoluble carrier, the first partner, the measurement object and the labeled second partner is separated from a portion not containing the complex. Then, signals originating from the labeled substance contained in either of the separated parts are detected. According to this method, the whole blood can be used as such without pre-treatment as the specimen, and the measurement object in the whole blood specimen can be measured quickly.
(FR)
Une quantité appropriée d'un échantillon de sang entier est maintenue en contact avec un support insoluble recouvert d'une première substance associée pouvant se lier spécifiquement à un objet de mesure pour un court laps de temps. Après que la combinaison de l'objet avec la première substance associée sur le support insoluble est mise en contact avec une seconde substance associée par liaison spécifique à l'objet, le complexe qui en résulte comprenant le support insoluble, la première substance associée, l'objet à mesurer et la seconde substance associée marquée est séparé d'une partie ne contenant pas le complexe. Ensuite, des signaux émanant de la substance marquée contenue dans l'une ou l'autre des parties séparées sont détectés. Selon cette méthode, le sang entier peut être utilisé en tant que tel sans prétraitement de l'échantillon et l'objet à mesurer dans l'échantillon de sang entier peut être mesuré rapidement.
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