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1. WO1996004388 - NOVEL COMPOUNDS

Publication Number WO/1996/004388
Publication Date 15.02.1996
International Application No. PCT/EP1995/003036
International Filing Date 28.07.1995
Chapter 2 Demand Filed 05.02.1996
IPC
A61K 38/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
C07K 14/54 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
52Cytokines; Lymphokines; Interferons
54Interleukins (IL)
C07K 16/00 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
CPC
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
C07K 14/5406
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
52Cytokines; Lymphokines; Interferons
54Interleukins [IL]
5406IL-4
C07K 16/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
C07K 2319/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
2319Fusion polypeptide
Applicants
  • SMITHKLINE BEECHAM PLC [GB/GB]; New Horizons Court Brentford Middlesex TW8 9EP, GB (AllExceptUS)
  • SMITHKLINE BEECHAM CORPORATION [US/US]; One Franklin Plaza P.O. Box 7929 Philadelphia, PA 19103, US (AllExceptUS)
  • BROWNE, Michael, Joseph [GB/GB]; GB (UsOnly)
  • MURPHY, Kay, Elizabeth [GB/GB]; GB (UsOnly)
  • CHAPMAN, Conrad, Gerald [GB/GB]; GB (UsOnly)
  • CLINKENBEARD, Helen, Elizabeth [US/GB]; GB (UsOnly)
  • YOUNG, Peter, Ronald [US/US]; US (UsOnly)
  • SHATZMAN, Allan, Richard [US/US]; US (UsOnly)
Inventors
  • BROWNE, Michael, Joseph; GB
  • MURPHY, Kay, Elizabeth; GB
  • CHAPMAN, Conrad, Gerald; GB
  • CLINKENBEARD, Helen, Elizabeth; GB
  • YOUNG, Peter, Ronald; US
  • SHATZMAN, Allan, Richard; US
Agents
  • WEST, Vivien; SmithKline Beecham Corporate Intellectual Property SB House, Great West Road Brentford Middlesex TW8 9BD, GB
  • GIDDINGS, Peter, John; SmithKline Beecham Corporate Intellectual Property SB House Great West Road Brentford, Middlesex TW8 9BD, GB
Priority Data
08/468,29706.06.1995US
9415379.829.07.1994GB
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) NOVEL COMPOUNDS
(FR) NOUVEAUX COMPOSES
Abstract
(EN)
A soluble protein having IL4 and/or IL13 antagonist or partial antagonist activity comprises an IL4 mutant or variant fused to at least one human immunoglobulin constant domain or fragment thereof.
(FR)
Protéine soluble ayant une activité antagoniste complète ou partielle de IL4 (interleukine 4) et/ou de IL13, qui comprend un variant ou mutant de IL4 fusionné avec au moins un domaine constant d'immunoglobuline humaine ou fragment dudit domaine.
Also published as
CZPV1997-256
KR1019970700613
NO19970374
NZ292124
Other related publications
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