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Machine translation
1. (WO1996004306) MUTEINS OF MAMMALIAN CYTOKINES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1996/004306    International Application No.:    PCT/US1995/008950
Publication Date: 15.02.1996 International Filing Date: 31.07.1995
IPC:
A61K 38/00 (2006.01), C07K 14/54 (2006.01), C07K 14/55 (2006.01)
Applicants: SCHERING CORPORATION [US/US]; 2000 Galloping Hill Road, Kenilworth, NJ 07033 (US)
Inventors: ZURAWSKI, Sandra, M.; (US).
ZURAWSKI, Gerard; (US)
Agent: FOULKE, Cynthia, L.; Schering-Plough Corporation, Patent Dept. K-6-1 1990, 2000 Galloping Hill Road, Kenilworth, NJ 07033-0530 (US)
Priority Data:
08/284,393 01.08.1994 US
Title (EN) MUTEINS OF MAMMALIAN CYTOKINES
(FR) MUTEINES DE CYTOKINES DE MAMMIFERE
Abstract: front page image
(EN)Methods for screening for partial agonists and for antagonists of mammalian cytokines. Particular positions of natural cytokines are identified as critical in providing these receptor mediated properties. Specific embodiments demonstrate properties of variations at these positions.
(FR)L'invention concerne des tests rapides pour évaluer les propriétés d'agonistes partiels et d'antagonistes de cytokines de mammifère. On a identifié les positions particulières de cytokines naturelles qui sont critiques pour assurer ces propriétés au niveau des récepteurs. Des formes d'exécution particulières permettent de démontrer les effets de variations dans ces positions sur ces propriétés.
Designated States: AM, AU, BB, BG, BR, BY, CA, CN, CZ, EE, FI, GE, HU, IS, JP, KG, KR, KZ, LK, LR, LT, LV, MD, MG, MN, MX, NO, NZ, PL, RO, RU, SG, SI, SK, TJ, TM, TT, UA, UZ, VN.
African Regional Intellectual Property Organization (KE, MW, SD, SZ, UG)
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)