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Machine translation
1. (WO1996004277) PYRROLINONE-BASED PEPTIDOMIMETICS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1996/004277    International Application No.:    PCT/US1995/009752
Publication Date: 15.02.1996 International Filing Date: 02.08.1995
Chapter 2 Demand Filed:    04.03.1996    
IPC:
C07D 207/36 (2006.01)
Applicants: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA [US/US]; Center for Technology Transfer, Suite 300, 3700 Market Street, Philadelphia, PA 19104-3147 (US)
Inventors: HIRSCHMANN, Ralph, F.; (US).
SMITH, Amos, B., III; (US).
SPRENGELER, Paul; (US).
HOLCOMB, Ryan, C.; (US).
KEENAN, Terence; (US).
WOOD, John, L.; (US).
GUZMAN, Mark; (US).
PASTERNAK, Alexander; (US)
Agent: ELDERKIN, Dianne, B.; Woodcock Washburn Kurtz Mackiewicz & Norris, 46th floor, 1 Liberty Place, Philadelphia, PA 19103 (US)
Priority Data:
08/285,027 02.08.1994 US
Title (EN) PYRROLINONE-BASED PEPTIDOMIMETICS
(FR) AGENTS PEPTIDOMIMETIQUES A BASE DE PYRROLINONES
Abstract: front page image
(EN)Novel pyrrolinone-based compounds mimic or inhibit the biological and/or chemical activity of peptides, including peptide $g(b)-strand conformations. Certain compounds contain functionalized pyrrolinone units in place of one or more amino acids of a target peptide.
(FR)Cette invention se rapporte à de nouveaux composés à base de pyrrolinones, qui imitent ou inhibent l'activité biologique et/ou chimique des peptides, y compris les conformations des brins $g(b) de peptides. Certains de ces composés contiennent des unités pyrrolinones fonctionnalisées à la place d'un ou de plusieurs acides aminés d'un peptitde cible.
Designated States: CA, JP.
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE).
Publication Language: English (EN)
Filing Language: English (EN)