Processing

Please wait...

Settings

Settings

1. WO1996004257 - CRYSTALLINE FORM OF AN ANTIFUNGAL AZOLE

Publication Number WO/1996/004257
Publication Date 15.02.1996
International Application No. PCT/GB1995/001816
International Filing Date 01.08.1995
Chapter 2 Demand Filed 19.02.1996
IPC
C07D 521/00 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
521Heterocyclic compounds containing unspecified hetero rings
CPC
C07D 231/12
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
231Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
02not condensed with other rings
10having two or three double bonds between ring members or between ring members and non-ring members
12with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
C07D 233/56
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
233Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
54having two double bonds between ring members or between ring members and non-ring members
56with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
C07D 249/08
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
249Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
02not condensed with other rings
081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Applicants
  • ZENECA LIMITED [GB/GB]; 15 Stanhope Gate London W1Y 6LN, GB (AllExceptUS)
  • MOCHIDA PHARMACEUTICAL CO. LTD. [JP/JP]; 7, Yotsuya 1-chome Shinjuku-ku Tokyo 160, JP (KR, SG)
  • LADD, Richard, Maurice [GB/GB]; GB (UsOnly)
  • CHEETHAM, Francis, David [GB/GB]; GB (UsOnly)
  • MOBBS, Bryan, Edward [GB/GB]; GB (UsOnly)
Inventors
  • LADD, Richard, Maurice; GB
  • CHEETHAM, Francis, David; GB
  • MOBBS, Bryan, Edward; GB
Agents
  • DENERLEY, Paul, Millington; Intellectual Property Group Intellectual Property Dept. ZENECA Pharmaceuticals Mereside, Alderley Park Macclesfield, Cheshire SK10 4TG, GB
Priority Data
9415617.102.08.1994GB
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) CRYSTALLINE FORM OF AN ANTIFUNGAL AZOLE
(FR) FORME CRISTALLINE D'UN AZOLE ANTIFONGIQUE
Abstract
(EN)
A crystalline form of the antifungal agent (+)-2-(2,4-difluorophenyl)-1-[3-[(E)-4-(2,2,3,3-tetrafluoropropoxy)-styryl]-1H-1,2,4-triazol-1-yl]-3- (1H-1,2,4-triazol-1-yl)propan-2-ol (code D0870) is described. Furthermore processes for the preparation thereof, to pharmaceutical compositions comprising said crystalline form and to the use thereof in therapy are described.
(FR)
L'invention concerne une forme cristalline de l'agent antifongique (+)-2-(2,4-difluorophényle)-1-(3-((E)-4-(2,2,3,3-tétrafluoropropoxy)-styryle)-1H-1,2,4-triazole-1-yle)-3-(1H-1,2,4-triazole-1-yle)propane-2-ol (code D0870). Elle concerne également des procédés servant à la préparer, des compositions pharmaceutiques comprenant ladite forme cristalline, ainsi que son utilisation thérapeutique.
Other related publications
Latest bibliographic data on file with the International Bureau