Processing

Please wait...

Settings

Settings

1. WO1996004251 - HETEROCYCLIC COMPOUND

Publication Number WO/1996/004251
Publication Date 15.02.1996
International Application No. PCT/JP1995/001478
International Filing Date 25.07.1995
Chapter 2 Demand Filed 29.01.1996
IPC
C07D 209/48 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
209Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
02condensed with one carbocyclic ring
44Iso-indoles; Hydrogenated iso-indoles
48with oxygen atoms in positions 1 and 3, e.g. phthalimide
C07D 235/06 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
235Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
02condensed with carbocyclic rings or ring systems
04Benzimidazoles; Hydrogenated benzimidazoles
06with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
C07D 235/08 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
235Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
02condensed with carbocyclic rings or ring systems
04Benzimidazoles; Hydrogenated benzimidazoles
06with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
08Radicals containing only hydrogen and carbon atoms
C07D 235/12 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
235Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
02condensed with carbocyclic rings or ring systems
04Benzimidazoles; Hydrogenated benzimidazoles
06with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
12Radicals substituted by oxygen atoms
C07D 235/16 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
235Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
02condensed with carbocyclic rings or ring systems
04Benzimidazoles; Hydrogenated benzimidazoles
06with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
16Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
C07D 235/26 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
235Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
02condensed with carbocyclic rings or ring systems
04Benzimidazoles; Hydrogenated benzimidazoles
24with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
26Oxygen atoms
CPC
C07D 209/48
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
209Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
02condensed with one carbocyclic ring
44Iso-indoles; Hydrogenated iso-indoles
48with oxygen atoms in positions 1 and 3, e.g. phthalimide
C07D 235/06
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
235Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
02condensed with carbocyclic rings or ring systems
04Benzimidazoles; Hydrogenated benzimidazoles
06with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
C07D 235/08
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
235Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
02condensed with carbocyclic rings or ring systems
04Benzimidazoles; Hydrogenated benzimidazoles
06with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
08Radicals containing only hydrogen and carbon atoms
C07D 235/12
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
235Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
02condensed with carbocyclic rings or ring systems
04Benzimidazoles; Hydrogenated benzimidazoles
06with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
12Radicals substituted by oxygen atoms
C07D 235/16
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
235Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
02condensed with carbocyclic rings or ring systems
04Benzimidazoles; Hydrogenated benzimidazoles
06with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
16Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
C07D 235/26
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
235Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
02condensed with carbocyclic rings or ring systems
04Benzimidazoles; Hydrogenated benzimidazoles
24with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
26Oxygen atoms
Applicants
  • FUJISAWA PHARMACEUTICAL CO., LTD. [JP/JP]; 4-7, Doshomachi 3-chome Chuo-ku Osaka-shi Osaka 541, JP (AllExceptUS)
  • OKU, Teruo [JP/JP]; JP (UsOnly)
  • KAYAKIRI, Hiroshi [JP/JP]; JP (UsOnly)
  • SATOH, Shigeki [JP/JP]; JP (UsOnly)
  • ABE, Yoshito [JP/JP]; JP (UsOnly)
  • SAWADA, Yuki [JP/JP]; JP (UsOnly)
  • INOUE, Takayuki [JP/JP]; JP (UsOnly)
  • TANAKA, Hirokazu [JP/JP]; JP (UsOnly)
Inventors
  • OKU, Teruo; JP
  • KAYAKIRI, Hiroshi; JP
  • SATOH, Shigeki; JP
  • ABE, Yoshito; JP
  • SAWADA, Yuki; JP
  • INOUE, Takayuki; JP
  • TANAKA, Hirokazu; JP
Agents
  • SEKI, Hideo; Fujisawa Pharmaceutical Co., Ltd. Osaka Factory 1-6, Kashima 2-chome Yodogawa-ku, Osaka-shi Osaka 532, JP
Priority Data
6/18254103.08.1994JP
7/5742716.03.1995JP
Publication Language Japanese (JA)
Filing Language Japanese (JA)
Designated States
Title
(EN) HETEROCYCLIC COMPOUND
(FR) COMPOSE HETEROCYCLIQUE
Abstract
(EN)
A heterocyclic compound represented by general formula (I) and a salt thereof; a process for producing the same; and a medicinal composition containing the same and useful for preventing and/or treating diseases of man or animal induced by bradykinin or an analog thereof. In said formula, a group represented by (a) is a group represented by (b), etc.; X represents O, S, or N-R5; R1 represents lower alkyl, etc.; R5 represents hydrogen, lower alkyl, etc.; R2 represents hydrogen, halogen, lower alkyl, etc.; R3 represents halogen, lower alkyl, etc.; R4 represents amino which may appropriately be substituted; and A represents lower alkylene.
(FR)
L'invention concerne un composé hétérocyclique représenté par la formule générale (I) ou un sel de celui-ci, un procédé pour le produire, et une composition médicinale le contenant et utile pour prévenir et/ou traiter des maladies chez l'homme ou les animaux, induites par la bradykinine ou un analogue de celle-ci. Dans la formule (I), le groupe représenté par (a) correspond à la formule (b), X représente O, S, ou N-R5, R1 représente alkyle inférieur, etc., R5 représente hydrogène, alkyle inférieur, etc, R2 représente hydrogène, halogène, alkyle inférieur, etc, R3 représente halogène, alkyle inférieur, etc., R4 représente amino qui peut être substitué d'une manière appropriée et A représente un alkylène inférieur.
Latest bibliographic data on file with the International Bureau