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1. WO1996003991 - COMPOSITIONS CONTAINING PROSTAGLANDIN E1 AND/OR TROXERUTINE COMPLEXED WITH PHOSPHATIDYLCHOLINE FOR TOPICAL TREATMENT OF ERECTILE IMPOTENCE

Publication Number WO/1996/003991
Publication Date 15.02.1996
International Application No. PCT/IB1995/000584
International Filing Date 25.07.1995
IPC
A61K 9/127 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
10Dispersions; Emulsions
127Liposomes
A61K 31/557 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
557Eicosanoids, e.g. leukotrienes
A61K 31/70 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
CPC
A61K 31/557
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
557Eicosanoids, e.g. leukotrienes ; or prostaglandins
A61K 31/70
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
A61K 47/544
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
50the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
51the non-active ingredient being a modifying agent
54the modifying agent being an organic compound
543Lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine
544Phospholipids
A61K 9/127
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
10Dispersions; Emulsions
127Liposomes
A61P 15/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
15Drugs for genital or sexual disorders
10for impotence
Y10S 514/937
YSECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
10TECHNICAL SUBJECTS COVERED BY FORMER USPC
STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
514Drug, bio-affecting and body treating compositions
937Dispersion or emulsion
Applicants
  • INPHARMA S.A. [CH/CH]; Via F. Borromini 3 CH-6900 Lugano, CH (AllExceptUS)
  • CURRI, Sergio [IT/IT]; IT (UsOnly)
Inventors
  • CURRI, Sergio; IT
Agents
  • MASPOLI, René, A.; Patentanwaltsbureau R.A. Maspoli Postfach/Witikonerstrasse 315 CH-8053 Zürich, CH
Priority Data
2454/94-705.08.1994CH
3809/94-116.12.1994CH
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) COMPOSITIONS CONTAINING PROSTAGLANDIN E1 AND/OR TROXERUTINE COMPLEXED WITH PHOSPHATIDYLCHOLINE FOR TOPICAL TREATMENT OF ERECTILE IMPOTENCE
(FR) COMPOSITIONS CONTENANT DE LA PROSTAGLANDINE E1 ET/OU DE LA TROXERUTINE COMPLEXEE(S) AVEC DE LA PHOSPHATIDYLCHOLINE POUR LE TRAITEMENT TOPIQUE DE L'IMPUISSANCE SEXUELLE
Abstract
(EN)
Description of pharmaceutical or cosmetic compositions aimed at improving the local microcirculation of the penis for chronic topical treatment of vascular impotence due to vascular causes, with main impairment of the arterial-arteriolar afferents of the cavernous bodies. The new pharmacological properties of the complex between PGE1 and/or Troxerutine with Phosphatidylcholine are administered locally on the skin of the penis; the activity is obtained using the T.E.B. system according to Curri.
(FR)
L'invention concerne des compositions pharmaceutiques ou cosmétiques destinées à être utilisées pour améliorer la microcirculation locale du pénis, pour le traitement topique prolongé de l'impuissance due à des raisons vasculaires, notamment une altération majeure des artères et des artérioles afférentes des corps caverneux. Le complexe formé par la PGE1 et/ou la troxerutine avec la phosphatidylcholine, lequel présente de nouvelles propriétés pharmacologiques, est appliqué localement sur la peau du pénis. L'activité est obtenue au moyen du système T.E.B. (Trans-Epidermal Barrier) selon Curri.
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