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1. (WO1996003977) A LIPOSOMAL DELIVERY SYSTEM FOR BIOLOGICALLY ACTIVE AGENTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1996/003977    International Application No.:    PCT/US1995/009867
Publication Date: 15.02.1996 International Filing Date: 04.08.1995
Chapter 2 Demand Filed:    14.02.1996    
IPC:
A61K 9/127 (2006.01), A61K 48/00 (2006.01), C12N 15/88 (2006.01)
Applicants: THE GOVERNMENT OF THE UNITED STATES OF AMERICA, represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES [US/US]; National Institutes of Health, Office of Technology Transfer, Suite 325, 6011 Executive Boulevard, Rockville, MD 20852 (US) (For All Designated States Except US).
THIERRY, Alain, R. [FR/US]; (US) (For US Only)
Inventors: THIERRY, Alain, R.; (US)
Agent: FEILER, William, S.; Morgan & Finnegan, L.L.P., 345 Park Avenue, New York, NY 10154 (US)
Priority Data:
08/286,730 05.08.1994 US
Title (EN) A LIPOSOMAL DELIVERY SYSTEM FOR BIOLOGICALLY ACTIVE AGENTS
(FR) SYSTEME D'ADMINISTRATION D'AGENTS BIOLOGIQUEMENT ACTIFS A L'AIDE_DE LIPOSOMES
Abstract: front page image
(EN)The present invention is directed to a liposomal preparation which is based on specific lipid components. The liposomal compounds are also combined with a biologically active agent, forming liposomal compounds. These compounds are useful in drug delivery, where specific therapeutic compounds are provided in the liposomes. The specific lipid components of the present invention provide a highly efficient and stable delivery system for nucleic acids. Consequently, one embodiment of the invention provide the liposomal preparations which are suitable for use in gene therapy.
(FR)La présente invention se rapporte à une préparation liposomique basée sur des composants lipidiques spécifiques. Les composés liposomiques sont également combinés à un agent biologiquement actif pour former des liposomes. Ces composés sont utilisés dans l'administration de médicaments, les composés thérapeutiques spécifiques étant introduits dans les liposomes. Les composés lipidiques de l'invention constituent un système d'administration très efficace et stable pour les acides nucléiques. En conséquence, un mode de réalisation de l'invention offre des préparations liposomiques appropriées pour être utilisées en thérapie génique.
Designated States: AM, AT, AU, BB, BG, BR, BY, CA, CH, CN, CZ, DE, DK, EE, ES, FI, GB, GE, HU, IS, JP, KE, KG, KP, KR, KZ, LK, LR, LT, LU, LV, MD, MG, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, TJ, TM, TT, UA, UG, US, UZ, VN.
African Regional Intellectual Property Organization (KE, MW, SD, SZ, UG)
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)