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1. WO1996003522 - UBIQUITIN-LYTIC PEPTIDE FUSION GENE CONSTRUCTS, PROTEIN PRODUCTS DERIVING THEREFROM, AND METHODS OF MAKING AND USING SAME

Publication Number WO/1996/003522
Publication Date 08.02.1996
International Application No. PCT/US1995/009338
International Filing Date 24.07.1995
Chapter 2 Demand Filed 21.02.1996
IPC
C07K 14/00 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
C07K 14/415 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
415from plants
C07K 14/435 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
C07K 14/46 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
C07K 14/47 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
C12N 15/82 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
79Vectors or expression systems specially adapted for eukaryotic hosts
82for plant cells
CPC
C07K 14/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
C07K 14/415
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
415from plants
C07K 14/435
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
C07K 14/46
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
C07K 14/4723
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
4701not used
4723Cationic antimicrobial peptides, e.g. defensins
C07K 2319/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
2319Fusion polypeptide
Applicants
  • DEMETER BIOTECHNOLOGIES, LTD. [US/US]; Suite 19-D 905 W. Main Street Brightleaf Square Durham, NC 27701, US
Inventors
  • JAYNES, Jesse; US
Agents
  • NORRIS, Lawrence, G. ; Rothwell, Figg, Ernst & Kurz Suite 701 East 555 13th Street, N.W. Washington, DC 20004, US
Priority Data
08/279,47222.07.1994US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) UBIQUITIN-LYTIC PEPTIDE FUSION GENE CONSTRUCTS, PROTEIN PRODUCTS DERIVING THEREFROM, AND METHODS OF MAKING AND USING SAME
(FR) PRODUIT D'ASSEMBLAGE DE GENES PAR FUSION DE PEPTIDES UBIQUITINE-LYTIQUES, PRODUITS PROTEIQUES EN DERIVANT ET LEURS PROCEDES D'OBTENTION ET D'UTILISATION
Abstract
(EN)
Stabilized ubiquitin-lytic peptide fusion polypeptides and a method of making the same by sub-cloning nucleic acid sequences coding for lytic peptides into a plasmid vector comprising a promoter and ubiquitin polypeptide coding sequence, wherein the ubiquitin polypeptide sequence is linked to the 5' end of the lytic peptide nucleic acid sequence and is translated as a fusion polypeptide.
(FR)
Polypeptides stabilisés de fusion du peptide ubiquitine-lytique et leur procédé d'obtention par sous-clonage de séquences d'acide nucléique codant pour des peptides lytiques dans un vecteur plasmidique comportant un promoteur et une séquence de codage d'un polypeptide d'ubiquitine, dans lequel la séquence du polypeptide d'ubiquitine est fixée à l'extrémité 5' de la séquence de l'acide nucléique du peptide lytique et se trouve traduite en polypeptide de fusion.
Also published as
Latest bibliographic data on file with the International Bureau