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1. WO1996003432 - NOVEL PROCESS FOR THE PRODUCTION OF BIOLOGICALLY ACTIVE DIMERIC PROTEIN

Publication Number WO/1996/003432
Publication Date 08.02.1996
International Application No. PCT/EP1995/002718
International Filing Date 12.07.1995
Chapter 2 Demand Filed 13.01.1996
IPC
A61K 38/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
C07K 1/113 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
1General processes for the preparation of peptides
107by chemical modification of precursor peptides
113without change of the primary structure
C07K 14/495 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
475Growth factors; Growth regulators
495Transforming growth factor (TGF)
CPC
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
C07K 1/1133
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
1General methods for the preparation of peptides ; , i.e. processes for the organic chemical preparation of peptides or proteins of any length
107by chemical modification of precursor peptides
113without change of the primary structure
1133by redox-reactions involving cystein/cystin side chains
C07K 14/495
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
475Growth factors; Growth regulators
495Transforming growth factor [TGF]
Applicants
  • NOVARTIS AG [CH/CH]; Schwarzwaldallee 215 CH-4058 Basel, CH (AllExceptUS)
  • CERLETTI, Nico [CH/CH]; CH (UsOnly)
Inventors
  • CERLETTI, Nico; CH
Common Representative
  • NOVARTIS AG; Patent and Trademark Dept. Klybeckstrasse 141 CH-4002 Basle, CH
Priority Data
94810438.525.07.1994EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) NOVEL PROCESS FOR THE PRODUCTION OF BIOLOGICALLY ACTIVE DIMERIC PROTEIN
(FR) NOUVEAUX PROCEDES DE PRODUCTION D'UNE PROTEINE DIMERE BIOLOGIQUEMENT ACTIVE
Abstract
(EN)
The present invention relates to a folding process for the preparation of biologically active, dimeric TGF-$g(b) (transforming Growth Factor type $g(b))-like protein.
(FR)
La présente invention concerne un procédé de repliement permettant la préparation d'une protéine dimère, biologiquement active, semblable au facteur de croissance transformant de type $g(b) (TGF-$g(b)).
Also published as
FI970229
NO19970325
NZ290373
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