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1. WO1996003141 - PHARMACEUTICAL COMPOSITIONS COMPRISING A CHIMAERIC TNF BINDING PROTEIN

Publication Number WO/1996/003141
Publication Date 08.02.1996
International Application No. PCT/EP1995/002788
International Filing Date 15.07.1995
Chapter 2 Demand Filed 06.02.1996
IPC
A61K 38/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
C07K 14/715 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
705Receptors; Cell surface antigens; Cell surface determinants
715for cytokines; for lymphokines; for interferons
CPC
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
A61P 25/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
A61P 37/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37Drugs for immunological or allergic disorders
C07K 14/7151
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
705Receptors; Cell surface antigens; Cell surface determinants
715for cytokines; for lymphokines; for interferons
7151for tumor necrosis factor [TNF], for lymphotoxin [LT]
C07K 2319/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
2319Fusion polypeptide
Applicants
  • F. HOFFMANN-LA ROCHE AG [CH/CH]; Grenzacherstrasse 124 CH-4002 Basle, CH (AllExceptUS)
  • BOOTH, Robert, Fredrick, Geoffrey [GB/GB]; GB (UsOnly)
  • LESSLAUER, Werner [CH/CH]; CH (UsOnly)
Inventors
  • BOOTH, Robert, Fredrick, Geoffrey; GB
  • LESSLAUER, Werner; CH
Agents
  • BRAUN, Axel; P.O. Box 3255 CH-4002 Basle, CH
Priority Data
94111455.522.07.1994EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) PHARMACEUTICAL COMPOSITIONS COMPRISING A CHIMAERIC TNF BINDING PROTEIN
(FR) COMPOSITIONS PHARMACEUTIQUES COMPRENANT UNE PROTEINE CHIMERE LIANT LE FACTEUR DE NECROSE TUMORALE
Abstract
(EN)
The present invention is directed to the use of a chimaeric TNF binding protein which comprises a soluble part of the human p55- or the p75-TNF-receptor and all or parts of the constant domains of the heavy or light chain of human immunoglobulin or of a pharmaceutically acceptable salt thereof for the preparation of a pharmaceutical composition for the treatment of autoimmune diseases.
(FR)
L'invention concerne l'utilisation d'une protéine chimère liant le facteur de nécrose tumorale (TNF), laquelle comporte une partie soluble du récepteur humain p55 ou p75 du TNF et la totalité ou des parties des domaines constants de la chaîne lourde ou légère de l'immunoglobuline humaine ou bien un sel pharmaceutiquement acceptable de celle-ci, pour la préparation d'une composition pharmaceutique destinée au traitement de maladies autoimmunes.
Also published as
CZPV1997-193
FI970247
NO19970264
Latest bibliographic data on file with the International Bureau