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Machine translation
1. (WO1996003093) BIOPROSTHETIC IMPLANTS AND METHOD OF MAKING AND USING SAME
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1996/003093    International Application No.:    PCT/US1995/009590
Publication Date: 08.02.1996 International Filing Date: 27.07.1995
Chapter 2 Demand Filed:    28.02.1996    
IPC:
A61L 27/36 (2006.01), A61L 27/38 (2006.01)
Applicants: VESELY, Ivan [CA/US]; (US).
NOSEWORTHY, Ronald [CA/CA]; (CA).
PRINGLE, Gordon [CA/CA]; (CA)
Inventors: VESELY, Ivan; (US).
NOSEWORTHY, Ronald; (CA).
PRINGLE, Gordon; (CA)
Agent: CORSO, Joseph, J.; Pearne, Gordon, McCoy & Granger, 1200 Leader Building, Cleveland, OH 44114 (US)
Priority Data:
08/282,059 28.07.1994 US
Title (EN) BIOPROSTHETIC IMPLANTS AND METHOD OF MAKING AND USING SAME
(FR) IMPLANTS BIOPROTHETIQUES ET LEUR PROCEDE DE FABRICATION ET D'UTILISATION
Abstract: front page image
(EN)The invention provides bioprosthetic implants from which the lipids have been removed by treatment with enzymes which degrade lipids, and methods of making and using the same. The enzymes include lipases and phospholipases. The removal of lipids from the bioprosthetic implants according to the present invention decreases the calcification of the bioprosthesis. The bioprosthetic implants preferably may be recellularized with fibroblasts or myofibroblasts before implanting the bioprosthesis in the body of a person.
(FR)L'invention concerne des implants bioprothétiques dont les lipides ont été éliminés par traitement par des enzymes dégradant les lipides. L'invention a également pour objet des procédés de production et d'utilisation de ces implants. Ces enzymes comprennent des lipases et des phospholipases. L'élimination des lipides de ces implants selon la présente invention réduit la calcification de la bioprothèse. Ces implants bioprothétiques peuvent, de préférence, être recellularisés par des fibroblastes ou des myofibroblastes avant leur implantation dans le corps d'un patient.
Designated States: AM, AT, AU, BB, BG, BR, BY, CA, CH, CN, CZ, DE, DK, EE, ES, FI, GB, GE, HU, IS, JP, KE, KG, KP, KR, KZ, LK, LR, LT, LU, LV, MD, MG, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, TJ, TM, TT, UA, UG, UZ, VN.
African Regional Intellectual Property Organization (KE, MW, SD, SZ, UG)
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)