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Machine translation
1. (WO1996002643) DENERVATED MUSCLE KINASE (DMK), A RECEPTOR OF THE TYROSINE KINASE SUPER FAMILY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1996/002643    International Application No.:    PCT/US1994/008039
Publication Date: 01.02.1996 International Filing Date: 20.07.1994
Chapter 2 Demand Filed:    16.02.1996    
IPC:
A61K 38/00 (2006.01), C07K 14/705 (2006.01)
Applicants: REGENERON PHARMACEUTICALS, INC. [US/US]; 777 Old Saw Mill River Road, Tarrytown, NY 10509 (US)
Inventors: VALENZUELA, David, M.; (US).
ROJAS, Eduardo, A.; (US)
Agent: KEMPLER, Gail; Regeneron Pharmaceuticals, Inc., 777 Old Saw Mill River Road, Tarrytown, NY 10591-6707 (US).
GOLDIN, Douglas, Michael; J.A. Kemp & Co., 14 South Square, Gray's Inn, London WC1R 5LX (GB)
Priority Data:
Title (EN) DENERVATED MUSCLE KINASE (DMK), A RECEPTOR OF THE TYROSINE KINASE SUPER FAMILY
(FR) KINASE DE MUSCLE ENERVE (DMK), UN RECEPTEUR DE LA SUPER FAMILLE DES TYROSINES KINASES
Abstract: front page image
(EN)The present invention provides for a gene, designated as $i(dmk), that encodes a novel tyrosine kinase receptor expressed in high levels in denervated muscle. The invention also provides assay systems that may be used to detect and/or measure ligands that bind the $i(dmk) gene product. The present invention also provides for diagnostic and therapeutic methods based on the interaction between Dmk and agents that initiate signal transduction through binding to Dmk.
(FR)L'invention concerne un gène, désigné sous l'appellation $i(dmk), codant du nouveau récepteur de la tyrosine kinase exprimé à des niveaux élevés dans le muscle énervé. L'invention concerne également des systèmes d'analyse utiles pour détecter et/ou mesurer des ligands liant le produit génique de $i(dmk). L'invention concerne encore des méthodes diagnostiques et thérapeutiques basées sur l'interaction entre Dmk et des agents initiant la transduction du signal par la liaison avec Dmk.
Designated States: AT, AU, BB, BG, BR, BY, CA, CH, CN, CZ, DE, DK, ES, FI, GB, HU, JP, KP, KR, KZ, LK, LU, LV, MG, MN, MW, NL, NO, NZ, PL, PT, RO, RU, SD, SE, SK, UA, UZ, VN.
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)