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1. WO1996002559 - GROWTH DIFFERENTIATION FACTOR-12

Publication Number WO/1996/002559
Publication Date 01.02.1996
International Application No. PCT/US1995/008745
International Filing Date 12.07.1995
Chapter 2 Demand Filed 01.02.1996
IPC
A61K 38/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
C07K 14/475 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
475Growth factors; Growth regulators
CPC
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
A61P 1/16
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
16for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
C07K 14/475
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
475Growth factors; Growth regulators
Applicants
  • THE JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE [US/US]; 720 Rutland Avenue Baltimore, MD 21205, US (AllExceptUS)
  • LEE, Se-Jin [US/US]; US (UsOnly)
  • ESQUELA, Aurora, F. [US/US]; US (UsOnly)
Inventors
  • LEE, Se-Jin; US
  • ESQUELA, Aurora, F.; US
Agents
  • HAILE, Lisa, A. ; Fish & Richardson P.C. Suite 1400 4225 Executive Square La Jolla, CA 92037, US
Priority Data
08/274,21513.07.1994US
08/311,37026.09.1994US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) GROWTH DIFFERENTIATION FACTOR-12
(FR) FACTEUR 12 DE CROISSANCE ET DE DIFFERENCIATION
Abstract
(EN)
Growth differentiation factor-12 (GDF-12) is disclosed along with its polynucleotide sequence and amino acid sequence. Also disclosed are diagnostic and therapeutic methods of using the GDF-12 polypeptide and polynucleotide sequences.
(FR)
L'invention se rapporte au facteur 12 de croissance et de différenciation (GDF-12), à sa séquence polynucléotidique et sa séquence d'acides aminés. L'invention se rapporte également à des méthodes diagnostiques et thérapeutiques d'utilisation des séquences polypeptidiques et polynucléotidiques du GDF-12.
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