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1. WO1996002524 - PHENYLCARBAMATE DERIVATIVES SUITABLE TO THE USE AS ANTICHOLINESTERASE SUBSTANCES

Publication Number WO/1996/002524
Publication Date 01.02.1996
International Application No. PCT/EP1995/002752
International Filing Date 13.07.1995
Chapter 2 Demand Filed 07.02.1996
IPC
C07C 271/44 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
271Derivatives of carbamic acid, i.e. compounds containing any of the groups the nitrogen atom not being part of nitro or nitroso groups
06Esters of carbamic acids
40having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings
42with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
44to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
C07C 271/56 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
271Derivatives of carbamic acid, i.e. compounds containing any of the groups the nitrogen atom not being part of nitro or nitroso groups
06Esters of carbamic acids
40having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings
56with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a ring other than a six-membered aromatic ring
C07C 271/58 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
271Derivatives of carbamic acid, i.e. compounds containing any of the groups the nitrogen atom not being part of nitro or nitroso groups
06Esters of carbamic acids
40having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings
58with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring
C07D 239/95 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
239Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
70condensed with carbocyclic rings or ring systems
72Quinazolines; Hydrogenated quinazolines
95with hetero atoms directly attached in positions 2 and 4
C07D 295/13 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
295Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
04with substituted hydrocarbon radicals attached to ring nitrogen atoms
12substituted by singly or doubly bound nitrogen atoms
125with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
13to an acyclic saturated chain
C07D 295/185 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
295Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
16acylated on ring nitrogen atoms
18by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
182Radicals derived from carboxylic acids
185from aliphatic carboxylic acids
CPC
C07C 2601/14
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
2601Systems containing only non-condensed rings
12with a six-membered ring
14The ring being saturated
C07C 271/44
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
271Derivatives of carbamic acids, i.e. compounds containing any of the groups , the nitrogen atom not being part of nitro or nitroso groups
06Esters of carbamic acids
40having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings
42with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
44to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
C07C 271/56
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
271Derivatives of carbamic acids, i.e. compounds containing any of the groups , the nitrogen atom not being part of nitro or nitroso groups
06Esters of carbamic acids
40having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings
56with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a ring other than a six-membered aromatic ring
C07C 271/58
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
271Derivatives of carbamic acids, i.e. compounds containing any of the groups , the nitrogen atom not being part of nitro or nitroso groups
06Esters of carbamic acids
40having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings
58with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring
C07D 239/95
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
239Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
70condensed with carbocyclic rings or ring systems
72Quinazolines; Hydrogenated quinazolines
95with hetero atoms directly attached in positions 2 and 4
C07D 295/13
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
295Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2.] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
04with substituted hydrocarbon radicals attached to ring nitrogen atoms
12substituted by singly or doubly bound nitrogen atoms
125with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
13to an acyclic saturated chain
Applicants
  • MEDIOLANUM FARMACEUTICI S.P.A. [IT/IT]; Via S. G. Cottolengo, 15/31 I-20143 Milano, IT (AllExceptUS)
  • TERNI, Patrizia [IT/IT]; IT (UsOnly)
  • MAIRANI, Lucia [IT/IT]; IT (UsOnly)
  • MANDELLI, Giacomina [IT/IT]; IT (UsOnly)
  • PAGELLA, Pier, Guiseppe [IT/IT]; IT (UsOnly)
  • MARCHESINI, Donata [IT/IT]; IT (UsOnly)
  • MAIORANA, Stefano [IT/IT]; IT (UsOnly)
  • BRUFANI, Mario [IT/IT]; IT (UsOnly)
Inventors
  • TERNI, Patrizia; IT
  • MAIRANI, Lucia; IT
  • MANDELLI, Giacomina; IT
  • PAGELLA, Pier, Guiseppe; IT
  • MARCHESINI, Donata; IT
  • MAIORANA, Stefano; IT
  • BRUFANI, Mario; IT
Agents
  • GERVASI, Gemma; Notarbartolo & Gervasi S.r.l. Viale Bianca Maria, 33 I-20122 Milano, IT
Priority Data
MI94A00149418.07.1994IT
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) PHENYLCARBAMATE DERIVATIVES SUITABLE TO THE USE AS ANTICHOLINESTERASE SUBSTANCES
(FR) DERIVES DE PHENYLCARBAMATE UTILISABLES COMME SUBSTANCES ANTICHOLINESTERASIQUES
Abstract
(EN)
Phenylcarbamate derivatives suitable to the use as anticholinesterase substances having general formula (I); wherein the meaning of R1-R7 and X substituents together with n will be defined in the text.
(FR)
L'invention concerne des dérivés de phénylcarbamate utilisables comme substances anticholinestérasiques et répondant à la formule générale (I); dans laquelle la signification des substituants R1-R7 et X ainsi que de n est donnée dans la description.
Also published as
Latest bibliographic data on file with the International Bureau