Processing

Please wait...

Settings

Settings

1. WO1996002278 - IMMUNONANOPARTICLES COATED WITH ANTI-BETA-2 MICROGLOBULIN MONOCLONAL ANTIBODIES

Publication Number WO/1996/002278
Publication Date 01.02.1996
International Application No. PCT/FR1995/000960
International Filing Date 18.07.1995
Chapter 2 Demand Filed 24.01.1996
IPC
A61K 9/51 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
48Preparations in capsules, e.g. of gelatin, of chocolate
50Microcapsules
51Nanocapsules
A61K 47/48 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
48the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
CPC
A61K 47/6849
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
50the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
51the non-active ingredient being a modifying agent
68the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
6835the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
6849the antibody targeting a receptor, a cell surface antigen or a cell surface determinant
A61K 47/6933
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
50the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
69the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
6921the form being a particulate, a powder, an adsorbate, a bead or a sphere
6927the form being a solid microparticle having no hollow or gas-filled cores
6929the form being a nanoparticle, e.g. an immuno-nanoparticle
6931the material constituting the nanoparticle being a polymer
6933the polymer being obtained by reactions only involving carbon to carbon, e.g. poly(meth)acrylate, polystyrene, polyvinylpyrrolidone or polyvinylalcohol
A61K 9/5138
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
48Preparations in capsules, e.g. of gelatin, of chocolate
50Microcapsules ; having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
51Nanocapsules; Nanoparticles;
5107Excipients; Inactive ingredients
513Organic macromolecular compounds; Dendrimers
5138obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
B82Y 5/00
BPERFORMING OPERATIONS; TRANSPORTING
82NANOTECHNOLOGY
YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
5Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Applicants
  • LABORATOIRES UPSA [FR/FR]; 304, avenue Docteur Jean-Bru F-47000 Agen, FR (AllExceptUS)
  • INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE [FR/FR]; 101, rue de Tolbiac F-75654 Paris Cédex 13, FR (AllExceptUS)
  • BRU-MAGNIEZ, Nicole [FR/FR]; FR (UsOnly)
  • CHERMANN, Jean-Claude [FR/FR]; FR (UsOnly)
  • LESCURE, François [FR/FR]; FR (UsOnly)
  • TEULON, Jean-Marie [FR/FR]; FR (UsOnly)
  • BRETON, Pascal [FR/FR]; FR (UsOnly)
  • GUILLON, Xavier [FR/FR]; FR (UsOnly)
Inventors
  • BRU-MAGNIEZ, Nicole; FR
  • CHERMANN, Jean-Claude; FR
  • LESCURE, François; FR
  • TEULON, Jean-Marie; FR
  • BRETON, Pascal; FR
  • GUILLON, Xavier; FR
Agents
  • PORTAL, Gérard ; Cabinet Beau-de-Loménie 158, rue de l'Université F-75340 Paris Cédex 07, FR
Priority Data
94/0885218.07.1994FR
Publication Language French (FR)
Filing Language French (FR)
Designated States
Title
(EN) IMMUNONANOPARTICLES COATED WITH ANTI-BETA-2 MICROGLOBULIN MONOCLONAL ANTIBODIES
(FR) IMMUNONANOPARTICULES REVETUES D'ANTICORPS MONOCLONAUX ANTI-BETA-2 MICROGLOBULINE
Abstract
(EN)
Immunonanoparticles consisting of nanoparticles of a polymeric methylidenemalonate compound coated with anti-$g(b)2 microglobulin antibodies, drugs containing same, and the use thereof for preventing and/or treating diseases caused by HIV infection, for making drugs for preventing and/or treating such diseases, as biological reactants, or in a method for screening for the presence of $g(b)2 microglobulin in free form or combined with viral particles in a biological fluid sample.
(FR)
L'invention concerne des immunanoparticules constituées de nanoparticules de polymère d'un composé méthylidène malonate revêtues d'anticorps anti-$g(b)2 microglobuline et les médicaments les contenant, ainsi que leur utilisation pour la prophylaxie et/ou le traitement de pathologies dues à une infection par le virus HIV, pour la fabrication de médicaments pour la prophylaxie et/ou le traitement desdites pathologies, en tant que réactifs biologiques, ou encore dans un procédé de détection de la présence de $g(b)2 microglobuline libre ou associée à des particules virales dans un échantillon de liquide biologique.
Also published as
Latest bibliographic data on file with the International Bureau