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1. WO1996002245 - NITRIC OXIDE SYNTHASE INHIBITORS FOR INHIBITING THE PRODUCTION OF AIRWAY MUCUS

Publication Number WO/1996/002245
Publication Date 01.02.1996
International Application No. PCT/GB1995/001657
International Filing Date 13.07.1995
Chapter 2 Demand Filed 12.01.1996
IPC
A61K 31/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
A61K 31/195 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19Carboxylic acids, e.g. valproic acid
195having an amino group
CPC
A61K 31/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
A61K 31/195
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic, hydroximic acids
19Carboxylic acids, e.g. valproic acid
195having an amino group
A61P 11/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
A61P 11/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
08Bronchodilators
Applicants
  • THE WELLCOME FOUNDATION LIMITED [GB/GB]; Glaxo Wellcome House Berkeley Avenue Greenford Middlesex UB6 0NN, GB (AllExceptUS)
  • ZIMMERMAN, Thomas, Paul [US/US]; US (UsOnly)
  • MOLINA, Luis [US/US]; US (UsOnly)
Inventors
  • ZIMMERMAN, Thomas, Paul; US
  • MOLINA, Luis; US
Agents
  • HAMMER, Catriona, McLeod; The Wellcome Foundation Limited Glaxo Wellcome House Berkeley Avenue Greenford Middlesex UB6 0NN, GB
Priority Data
275,16714.07.1994US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) NITRIC OXIDE SYNTHASE INHIBITORS FOR INHIBITING THE PRODUCTION OF AIRWAY MUCUS
(FR) INHIBITEURS DE SYNTHASE D'OXYDE NITRIQUE INHIBANT LES SECRETIONS DE MUCOSITES DES VOIES AERIENNES
Abstract
(EN)
The use of an NO synthase inhibitor, for example L-NMMA, in inhibiting the production of airway mucus secretion, e.g. in cystic fibrosis, chronic bronchitis and emphysema, is disclosed.
(FR)
L'invention concerne l'utilisation d'un inhibiteur de synthase d'oxyde nitrique, par exemple L-NMMA, afin d'inhiber les sécrétions de mucosités des voies aériennes, notamment, dans la mucoviscidose, la bronchite chronique et l'emphysème.
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