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1. WO1996002237 - NOVEL METHOD FOR PREPARING DRY PHARMACEUTICALS CAPABLE OF VIRTUALLY INSTANTANEOUS DISINTEGRATION, AND RESULTING PHARMACEUTICALS

Publication Number WO/1996/002237
Publication Date 01.02.1996
International Application No. PCT/FR1995/000947
International Filing Date 13.07.1995
IPC
A61K 9/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
A61K 9/20 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
20Pills, lozenges or tablets
CPC
A61K 9/0056
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0012Galenical forms characterised by the site of application
0053Mouth and digestive tract, i.e. intraoral and peroral administration
0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
A61K 9/2081
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
20Pills, tablets, ; discs, rods
2072characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
2081with microcapsules or coated microparticles according to A61K9/50
Applicants
  • VACHER, Dominique [FR/FR]; FR
Inventors
  • VACHER, Dominique; FR
Agents
  • BURTIN, Jean-François; Cabinet GEFIB 85, rue Anatole-France F-92300 Levallois-Perret, FR
Priority Data
94/0881115.07.1994FR
Publication Language French (FR)
Filing Language French (FR)
Designated States
Title
(EN) NOVEL METHOD FOR PREPARING DRY PHARMACEUTICALS CAPABLE OF VIRTUALLY INSTANTANEOUS DISINTEGRATION, AND RESULTING PHARMACEUTICALS
(FR) NOUVEAU PROCEDE DE REALISATION DE FORMES PHARMACEUTIQUES SECHES A DELITEMENT QUASIMENT INSTANTANE ET LES FORMES PHARMACEUTIQUES AINSI REALISEES
Abstract
(EN)
A method for preparing solid pharmaceuticals capable of virtually instantaneous disintegration for use in chemotherapy, wherein one or more active principles previously coated with a binder are mixed with a cellulose expanding agent and one or more water-soluble diluents before powder compression. Solid pharmaceuticals may thus be prepared.
(FR)
La présente invention se rapporte au domaine de la chimie thérapeutique. Elle a plus particulièrement pour objet un procédé de réalisation de formes pharmaceutiques solides à délitement quasi-instantané dans lequel le ou les principes actifs préalablement enrobés dans un agent liant sont mélangés à un agent gonflant du type cellulosique et à un ou plusieurs agents diluants hydrosolubles préalablement à la compression des poudres. Réalisation de formes pharmaceutiques solides.
Also published as
Latest bibliographic data on file with the International Bureau