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1. WO1996002234 - SELF-DESINTEGRATING COMPACT GRANULES USED IN GALENIC FORMS AND CONTAINING ACTIVE INSOLUBLE OR HARDLY SOLUBLE PRINCIPLES

Publication Number WO/1996/002234
Publication Date 01.02.1996
International Application No. PCT/ES1994/000073
International Filing Date 18.07.1994
IPC
A61K 9/16 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
14Particulate form, e.g. powders
16Agglomerates; Granulates; Microbeadlets
A61K 9/20 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
20Pills, lozenges or tablets
CPC
A61K 9/1617
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
14Particulate form, e.g. powders, ; Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
16Agglomerates; Granulates; Microbeadlets ; ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
1605Excipients; Inactive ingredients
1617Organic compounds, e.g. phospholipids, fats
A61K 9/1635
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
14Particulate form, e.g. powders, ; Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
16Agglomerates; Granulates; Microbeadlets ; ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
1605Excipients; Inactive ingredients
1629Organic macromolecular compounds
1635obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
A61K 9/2077
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
20Pills, tablets, ; discs, rods
2072characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
Applicants
  • CARVAJAL MARTIN, Luis Cipriano [ES/ES]; ES
  • LEDGER, Ian, Anthony, David [GB/BE]; BE
Inventors
  • CARVAJAL MARTIN, Luis Cipriano; ES
  • LEDGER, Ian, Anthony, David; BE
Agents
  • FORTEA LAGUNA, Juan José; Calle Domènec, 6 2º-2ª E-08190 St Cugat, ES
Priority Data
Publication Language Spanish (ES)
Filing Language Spanish (ES)
Designated States
Title
(EN) SELF-DESINTEGRATING COMPACT GRANULES USED IN GALENIC FORMS AND CONTAINING ACTIVE INSOLUBLE OR HARDLY SOLUBLE PRINCIPLES
(ES) GRANULOS COMPACTOS ALTAMENTE AUTODISGREGANTES PARA USO EN FORMAS GALENICAS CONTENIENDO PRINCIPIOS ACTIVOS INSOLUBLES O POCO SOLUBLES
(FR) GRANULES COMPACTS AUTO-DESINTEGRANTS S'UTILISANT DANS DES FORMES GALENIQUES CONTENANT DES PRINCIPES ACTIFS INSOLUBLES OU PEU SOLUBLES
Abstract
(EN)
Self-desintegrating compact granules used in galenic forms and containing insoluble or hardly soluble active principles, such as for example in tablets, capsules, bags or extemporaneous mixtures, characterized essentially in that they are comprised of an intimate and homogeneous mixture of finally divided active principle, an intumescent hygroscopic agent and an emulgent.
(ES)
Gránulos compactos autodisgregantes para uso en formas galénicas conteniendo principios activos insolubles o poco solubles, como por ejemplo en comprimidos, cápsulas, sobres o mezclas extemporáneas, que se caracteriza esencialmente por que se compone de una mezcla íntima y homogénea de Principio Activo finamente dividido, un agente higroscópico intumescente, y un emulgente.
(FR)
Granules compacts auto-désintégrants s'utilisant dans des formes galéniques contenant des principes actifs insolubles ou peu solubles, par exemple dans des comprimés, des capsules, des sachets ou des mélanges extemporanés, caractérisés essentiellement en ce qu'ils se composent d'un mélange intime et homogène d'un principe actif finement divisé, un agent hygroscopique intumescent, et un émulgent.
Also published as
Latest bibliographic data on file with the International Bureau