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1. WO1996002232 - COMPOSITION AND METHOD FOR ENHANCING TRANSDERMAL ELECTROTRANSPORT AGENT DELIVERY

Publication Number WO/1996/002232
Publication Date 01.02.1996
International Application No. PCT/US1995/008384
International Filing Date 29.06.1995
Chapter 2 Demand Filed 08.02.1996
IPC
A61K 9/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
CPC
A61K 9/0009
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
0009involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
Applicants
  • ALZA CORPORATION [US/US]; 950 Page Mill Road P.O. Box 10950 Palo Alto, CA 94303-0802, US
Inventors
  • GYORY, J., Richard; US
Agents
  • MILLER, D., Byron ; Alza Corporation P.O. Box 10950 Palo Alto, CA 94303-0802, US
Priority Data
08/274,61913.07.1994US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) COMPOSITION AND METHOD FOR ENHANCING TRANSDERMAL ELECTROTRANSPORT AGENT DELIVERY
(FR) COMPOSITION ET PROCEDE ACCROISSANT LA DIFFUSION PERCUTANEE PAR ELECTROTRANSPORT D'UNE SUBSTANCE
Abstract
(EN)
A composition comprises an agent to be delivered through a body surface and an electrotransport enhancer having a hydrophobic tail and a polar head of specific characteristics. An electrotransport delivery device (10) is also provided having a reservoir (16) comprising the agent to be delivered and the electrotransport enhancer of the invention. The electrotransport enhancers increase the electrotransport delivery rate of the agent through the surface while reducing the electrical resistance of the surface during electrotransport of the agent.
(FR)
Composition comprenant une substance devant être administrée par voie percutanée et un accélérateur d'électrotransport présentant une queue hydrophobe et une tête polaire ayant des caractéristiques spécifiques. Le dispositif d'administration par électrotransport (10) est muni d'un réservoir (16) contenant la substance à administrer et l'accélérateur. Les accélérateurs d'électrotransport accroissent la vitesse de passage de substances à travers la surface tout en réduisant la résistance superficielle pendant l'électrotransport desdites substances.
Also published as
Latest bibliographic data on file with the International Bureau