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1. WO1995034814 - PLASMA TREATMENT OF POLYMERIC MATERIALS TO ENHANCE IMMOBILIZATION OF ANALYTES THERETO

Publication Number WO/1995/034814
Publication Date 21.12.1995
International Application No. PCT/US1995/007500
International Filing Date 13.06.1995
Chapter 2 Demand Filed 11.01.1996
IPC
G01N 33/543 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
543with an insoluble carrier for immobilising immunochemicals
G01N 33/545 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
543with an insoluble carrier for immobilising immunochemicals
544the carrier being organic
545Synthetic resin
CPC
G01N 33/54393
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
543with an insoluble carrier for immobilising immunochemicals
54393Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
G01N 33/545
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
543with an insoluble carrier for immobilising immunochemicals
544the carrier being organic
545Synthetic resin
Applicants
  • ABBOTT LABORATORIES [US]/[US]
Inventors
  • BLACK, William, N.
Agents
  • DANCKERS, Andreas, M.
Priority Data
08/259,31113.06.1994US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) PLASMA TREATMENT OF POLYMERIC MATERIALS TO ENHANCE IMMOBILIZATION OF ANALYTES THERETO
(FR) TRAITEMENT AU PLASMA DE MATIERES POLYMERES AFIN D'AMELIORER L'IMMOBILISATION D'ANALYTE SUR CELLES-CI
Abstract
(EN)
A method is disclosed for treating the surface of a polymeric material of an assay device to increase the sensitivity of diagnostic assays and screening assays. The method involves the treatment of the surface of the polymeric material with unseparated oxygen plasma to increase the binding capability of an analyte or analyte-binding member to such surface. The treated polymeric material is utilized as a diagnostic assay device or screening assay device for determining the amount or presence of an analyte or analyte-binding member in a test sample.
(FR)
L'invention concerne un procédé de traitement de la surface d'une matière polymère d'un dispositif de dosage afin d'augmenter la sensibilité des dosages de diagnostic et de criblage. Le procédé consiste à traiter la surface de la matière polymère avec un plasma à oxygène non séparé afin d'augmenter la capacité de liaison d'un analyte ou d'un élément de liaison d'analyte à ladite surface. On utilise la matière polymère traitée en tant que dispositif de dosage ou de criblage pour diagnostic, afin de déterminer la quantité ou la présence d'un analyte ou d'un élément de liaison d'analyte dans un échantillon de test.
Also published as
Latest bibliographic data on file with the International Bureau