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1. WO1994029456 - HERPES SIMPLEX VIRUS TYPE-2 PROTEASE

Publication Number WO/1994/029456
Publication Date 22.12.1994
International Application No. PCT/US1994/005920
International Filing Date 25.05.1994
Chapter 2 Demand Filed 02.12.1994
IPC
C07K 16/08 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
08against material from viruses
C12N 9/50 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
14Hydrolases (3.)
48acting on peptide bonds, e.g. thromboplastin, leucine aminopeptidase (3.4)
50Proteinases
CPC
C07K 16/087
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
08against material from viruses
081from DNA viruses
085Herpetoviridae, e.g. pseudorabies virus, Epstein-Barr virus
087Herpes simplex virus
C12N 9/503
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9Enzymes; Proenzymes; Compositions thereof
14Hydrolases (3)
48acting on peptide bonds (3.4)
50Proteinases ; , e.g. Endopeptidases (3.4.21-3.4.25)
503derived from viruses
Applicants
  • ABBOTT LABORATORIES [US]/[US]
Inventors
  • STEFFY, Kevin, R.
  • KATI, Warren, M.
  • KATZ, Leonard
  • McGONIGAL, Thomas, P.
  • SARTHY, Aparna, V.
  • SCHOEN, Sharon, E.
Agents
  • CROWLEY, Steven, R.
Priority Data
08/073,81908.06.1993US
08/245,39023.05.1994US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) HERPES SIMPLEX VIRUS TYPE-2 PROTEASE
(FR) PROTEASE ASSOCIEE AU VIRUS DE L'HERPES DU TYPE 2
Abstract
(EN)
Protease activity associated with herpes simplex virus (HSV) type 2 was identified. The complete nucleotide and amino acid sequence of the protease was determined. The HSV-2 nucleic acid segment encoding the protease substrate ICP35 was also sequenced. Recombinant vectors and host cells for expressing the protease are also described.
(FR)
On a identifié l'activité de la protéase associée au virus de l'herpès du type 2. On a déterminé la séquence complète d'acides aminés et de nucléotides de la protéase. On a également séquencé le segment d'acide nucléique du virus de l'herpès du type 2 codant le substrat ICP35 de la protéase. Des vecteurs de recombinaison et des cellules hôtes destinés à exprimer la protéase sont égalements décrits.
Also published as
Latest bibliographic data on file with the International Bureau