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1. WO1994029455 - MUTANT POLYPEPTIDE OF PROTEIN KINASE C, NUCLEIC ACID SEQUENCES CODING FOR SAID POLYPEPTIDE AND USE THEREOF

Publication Number WO/1994/029455
Publication Date 22.12.1994
International Application No. PCT/FR1994/000686
International Filing Date 10.06.1994
Chapter 2 Demand Filed 14.12.1994
IPC
A61K 38/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
C12N 9/12 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
10Transferases (2.)
12transferring phosphorus containing groups, e.g. kinases (2.7)
CPC
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
C12N 9/12
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9Enzymes; Proenzymes; Compositions thereof
10Transferases (2.)
12transferring phosphorus containing groups, e.g. kinases (2.7)
Applicants
  • INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE [FR]/[FR] (AllExceptUS)
  • JOUBERT, Dominique [FR]/[FR] (UsOnly)
  • ALVARO, Véronique [FR]/[FR] (UsOnly)
  • LEVY, Laurence [FR]/[FR] (UsOnly)
Inventors
  • JOUBERT, Dominique
  • ALVARO, Véronique
  • LEVY, Laurence
Agents
  • GILLARD, Marie-Louise
Priority Data
93/0708911.06.1993FR
Publication Language French (FR)
Filing Language French (FR)
Designated States
Title
(EN) MUTANT POLYPEPTIDE OF PROTEIN KINASE C, NUCLEIC ACID SEQUENCES CODING FOR SAID POLYPEPTIDE AND USE THEREOF
(FR) POLYPEPTIDE MUTANT DE LA PROTEINE KINASE C, SEQUENCES D'ACIDES NUCLEIQUES CODANT POUR LEDIT POLYPEPTIDE ET LEURS UTILISATIONS
Abstract
(EN)
A mutant polypeptide of protein kinase C shows localised D 294 G mutation with respect to PKC$g(a). Nucleic acid sequences coding for said polypeptide nucleotide probes and antisense oligonucleotides are also disclosed. Application in cancer diagnosis or therapy.
(FR)
L'invention a pour objet un polypeptide mutant de la protéine kinase C qui possède, par rapport à la PKC$g(a), une mutation ponctuelle D 294 G. L'invention a également pour objet les séquences d'acides nucléiques qui codent pour ledit polypeptide, ainsi que des sondes nucléotidiques et des oligonucléotides antisens. Application: diagnostic ou traitement thérapeutique des cancers.
Also published as
Latest bibliographic data on file with the International Bureau