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Machine translation
1. (WO1994029309) SPIRO-SUBSTITUTED AZACYCLES AS NEUROKININ ANTAGONISTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1994/029309    International Application No.:    PCT/US1994/005545
Publication Date: 22.12.1994 International Filing Date: 17.05.1994
Chapter 2 Demand Filed:    17.11.1994    
IPC:
C07D 471/10 (2006.01), C07D 491/10 (2006.01), C07D 495/10 (2006.01)
Applicants: MERCK & CO., INC. [US/US]; 126 East Lincoln Avenue, Rahway, NJ 07065 (US) (For All Designated States Except US).
MacCOSS, Malcolm [GB/US]; (US) (For US Only).
MILLS, Sander, G. [US/US]; (US) (For US Only).
SHAH, Shrenik, K. [IN/US]; (US) (For US Only).
CHIANG, Yuan-Ching, P. [US/US]; (US) (For US Only).
DUNN, Patrick, T. [US/US]; (US) (For US Only).
KOYAMA, Hiroo [JP/US]; (US) (For US Only).
FINKE, Paul, E. [US/US]; (US) (For US Only).
QI, Hongbo [CN/US]; (US) (For US Only).
ROBICHAUD, Albert, J. [US/US]; (US) (For US Only)
Inventors: MacCOSS, Malcolm; (US).
MILLS, Sander, G.; (US).
SHAH, Shrenik, K.; (US).
CHIANG, Yuan-Ching, P.; (US).
DUNN, Patrick, T.; (US).
KOYAMA, Hiroo; (US).
FINKE, Paul, E.; (US).
QI, Hongbo; (US).
ROBICHAUD, Albert, J.; (US)
Common
Representative:
MERCK & CO., INC.; Patent Dept., 126 East Lincoln Avenue, Rahway, NJ 07065 (US)
Priority Data:
072,904 07.06.1993 US
Title (EN) SPIRO-SUBSTITUTED AZACYCLES AS NEUROKININ ANTAGONISTS
(FR) AZACYCLES SPIROSUBSTITUES ANTAGONISTES DE LA NEUROKININE
Abstract: front page image
(EN)Disclosed are spiro-substituted azacycles of formula (I), tachykinin receptor antagonists useful in the treatment of inflammatory diseases, pain or migraine, and asthma. In particular compounds of formula (I) are shown to be neurokinin antagonists.
(FR)Azacycles spirosubstitués de la formule I, antagonistes des récepteurs de la tachykinine, utiles dans le traitement de maladies inflammatoires, de la douleur ou de la migraine et de l'asthme. Et, en particulier, composés de la formule (I) s'avérant antagonistes de la neurokinine.
Designated States: AU, BB, BG, BR, BY, CA, CN, CZ, FI, HU, JP, KR, KZ, LK, LV, MG, MN, MW, NO, NZ, PL, RO, RU, SD, SI, SK, TT, UA, US, UZ.
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)