WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO1994028927) $i(PASTEURELLA HAEMOLYTICA) SUBUNIT VACCINE CONTAINING CAPSULAR POLYSACCHARIDE AND MURAMYL DIPEPTIDE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1994/028927    International Application No.:    PCT/US1994/006368
Publication Date: 22.12.1994 International Filing Date: 06.06.1994
Chapter 2 Demand Filed:    27.12.1994    
IPC:
A61K 39/102 (2006.01), A61K 39/39 (2006.01), G01N 33/569 (2006.01)
Applicants: THE UNITED STATES OF AMERICA, represented by THE S [US/US]; ECRETARY OF AGRICULTURE:, Washington, DC 20250 (US) (For All Designated States Except US).
VACSYN SA [FR/FR]; 33, boulevard du Général Martial-Valin, F-75015 Paris (FR) (For All Designated States Except US).
BROGDEN, Kim, A. [US/US]; (US) (For US Only).
CHEDID, Louis [FR/FR]; (US) (For US Only)
Inventors: BROGDEN, Kim, A.; (US).
CHEDID, Louis; (US)
Agent: PENDORF, Stephan, A.; Dominik & Stein, Suite 1000, 600 North West Shore Boulevard, Tampa, FL 33609 (US)
Priority Data:
08/075,064 10.06.1993 US
Title (EN) $i(PASTEURELLA HAEMOLYTICA) SUBUNIT VACCINE CONTAINING CAPSULAR POLYSACCHARIDE AND MURAMYL DIPEPTIDE
(FR) VACCIN A SOUS-UNITES CONTRE LA $i(PASTEURELLA HAEMOLYTICA) CONTENANT UN POLYSACCHARIDE CAPSULAIRE ET UN DIPEPTIDE DE MURAMYLE
Abstract: front page image
(EN)Protection of ruminants against bacterial pneumonia caused by $i(Pasteurella haemolytica) has been achieved with a subunit vaccine. The vaccine contains two principle components: capsular polysaccharide of $i(P. haemolytica) and a synthetic adjuvant, muramyl dipeptide. This vaccine prevented bacterial infection of the lungs of vaccinated animals upon challenge with $i(P. haemolytica). In contrast, animals that were not vaccinated or animals that were vaccinated with only capsular polysaccharide alone had severe lesions and high concentrations of $i(P. haemolytica) in the lungs.
(FR)La protection des ruminants contre la pneumonie bactérienne induite par la $i(Pasteurella haemolytica) est assurée au moyen d'un vaccin à sous-unités. Ledit vaccin contient deux composants principaux: un polysaccharide de $i(P. haemolytica) et un adjuvant synthétique, soit un dipeptide de muramyle. Ledit vaccin prévient l'infection bactérienne des poumons d'animaux vaccinés qui viendraient au contact de $i(P. haemolytica). En revanche, les animaux n'ayant pas été vaccinés ou les animaux ayant été vaccinés avec seulement un polysaccharide capsulaire présentent des lésions graves et des concentrations élevées de $i(P. haemolytica) dans les poumons.
Designated States: AT, AU, CA, US.
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE).
Publication Language: English (EN)
Filing Language: English (EN)