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1. (WO1994027975) 3-(MERCAPTOALKYL)- OR 3-(ALKYLTHIOALKYL)- PYRIMIDIN-2,4(1H, 3H)-DIONES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1994/027975    International Application No.:    PCT/CH1994/000089
Publication Date: 08.12.1994 International Filing Date: 16.05.1994
IPC:
C07D 239/557 (2006.01)
Applicants: PENTAPHARM AG [CH/CH]; Engelgasse 109, CH-4052 Basel (CH) (For All Designated States Except US).
LEISTNER, Siegfried [DE/DE]; (DE) (For US Only).
DRÖSSLER, Karl [DE/DE]; (DE) (For US Only).
STOCKER, Kurt [CH/CH]; (CH) (For US Only).
VIEWEG, Helmut [DE/DE]; (DE) (For US Only)
Inventors: LEISTNER, Siegfried; (DE).
DRÖSSLER, Karl; (DE).
STOCKER, Kurt; (CH).
VIEWEG, Helmut; (DE)
Agent: BRAUN, André; Murtengasse 5, CH-4051 Basel (CH)
Priority Data:
1541/93-1 21.05.1993 CH
Title (DE) 3-(MERCAPTOALKYL)- BZW. 3-(ALKYLTHIOALKYL)-PYRIMIDIN-2,4 (1H, 3H)-DIONE
(EN) 3-(MERCAPTOALKYL)- OR 3-(ALKYLTHIOALKYL)- PYRIMIDIN-2,4(1H, 3H)-DIONES
(FR) 3-(MERCAPTOALKYL)- OU 3-(ALKYLTHIOALKYL)-PYRIMIDIN-2,4(1H, 3H)-DIONES
Abstract: front page image
(DE)Es wurden 3-(Mercaptoalkyl)- bzw. 3-(Alkylthioalkyl)-pyrimidin-2,4(1H, 3H)-dione gefunden, die eine immunstimulierende und/oder immunrestaurative Wirkung aufweisen und/oder zur Behandlung von Krankheiten geeignet sind, deren Ursache ein durch exogene und/oder endogene Faktoren verminderte Phagozytoseaktivität von Granulozyten bzw. Makrophagen ist.
(EN)Disclosed are 3-(mercaptoalkyl)- or 3-(alkylthioalkyl)- pyrimidin-2,4(1H, 3H)-diones which exhibit an immune-stimulating and/or immune-restoring action and/or are suitable for use in the treatment of illnesses caused by phagocytose activity of granulocytes or macrophages reduced by exogenic and/or endogenic factors.
(FR)Des 3-(mercaptoalkyl)- ou 3-(alkylthioalkyl)-pyrimidin-2,4(1H, 3H)-diones ont un effet immuno-stimulant et/ou immuno-reconstituant et/ou sont utiles pour traiter des maladies dont la cause est une réduction de l'activité de phagocytose des granulocytes ou des macrophages provoquée par des facteurs exogènes et/ou endogènes.
Designated States: AT, AU, BB, BG, BR, BY, CA, CH, CN, CZ, DE, DK, ES, FI, GB, GE, HU, JP, KG, KP, KR, KZ, LK, LU, LV, MD, MG, MN, MW, NL, NO, NZ, PL, PT, RO, RU, SD, SE, SI, SK, TJ, TT, UA, US, UZ, VN.
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: German (DE)
Filing Language: German (DE)