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Machine translation
1. (WO1994027958) 4-AMIDINOPHENYLSULPHONAMIDES FOR THE TREATMENT OF THROMBO-EMBOLITIC CONDITIONS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1994/027958    International Application No.:    PCT/EP1994/001562
Publication Date: 08.12.1994 International Filing Date: 13.05.1994
Chapter 2 Demand Filed:    09.09.1994    
IPC:
A61K 38/00 (2006.01), C07C 311/42 (2006.01), C07C 311/46 (2006.01), C07K 5/06 (2006.01), C07K 5/083 (2006.01)
Applicants: BOEHRINGER MANNHEIM GMBH [DE/DE]; Sandhofer Strasse 116, D-68298 Mannheim (DE) (For All Designated States Except US).
VON DER SAAL, Wolfgang [DE/DE]; (DE) (For US Only).
LEINERT, Herbert [DE/DE]; (DE) (For US Only).
POLL, Thomas [DE/DE]; (DE) (For US Only).
STEGMEIER, Karlheinz [DE/DE]; (DE) (For US Only)
Inventors: VON DER SAAL, Wolfgang; (DE).
LEINERT, Herbert; (DE).
POLL, Thomas; (DE).
STEGMEIER, Karlheinz; (DE)
Agent: WEBER, Manfred; Boehringer Mannheim GmbH, Sandhoferstrasse 116, D-68298 Mannheim 31 (DE)
Priority Data:
P 43 16 922.8 20.05.1993 DE
Title (DE) 4-AMIDINOPHENYLSULFONAMIDE ZUR BEHANDLUNG VON THROMBOEMBOLISCHEN ERKRANKUNGEN
(EN) 4-AMIDINOPHENYLSULPHONAMIDES FOR THE TREATMENT OF THROMBO-EMBOLITIC CONDITIONS
(FR) 4-AMIDINOPHENYLSULFONAMIDES POUR LE TRAITEMENT DE MALADIES THROMBOEMBOLIQUES
Abstract: front page image
(DE)Verbindungen der Formel (I), in der A eine $g(a)-Aminosäure bedeutet, B eine Bindung oder eine $g(a)-Aminosäure bedeutet, R¿1?, R¿2? gleich oder verschieden sind und Wasserstoffatom, Phenyl-, Carboxyl oder C¿1?-C¿8?-Alkyloxycarbonyl bedeuten, sowie deren physiologisch verträgliche Salze, Hydrate, Solvate und optische Isomeren, Verfahren zu ihrer Herstellung und Arzneimittel, die diese Stoffe enthalten, zur Behandlung von thromboembolischen Erkrankungen.
(EN)The invention concerns compounds of the formula (I) in which A is an $g(a)-amino acid, B is a bond or an $g(a)-amino acid and R¿1? and R¿2?, which may be the same or different, are hydrogen, phenyl, carboxyl or (C¿1?-C¿8? alkoxy) carbonyl, plus their physiologically tolerated salts, hydrates, solvates and optical isomers. The invention also concerns methods of preparing such compounds and drugs containing them for use in the treatment of thrombo-embolitic conditions.
(FR)Composés de formule (I), dans laquelle A désigne un aminoacide $g(a), B désigne une liaison ou un aminoacide $g(a), R¿1?, R¿2? sont identiques ou différents et désignent un atome d'hydrogène, un phényle, un carboxyle ou un alkyloxy C¿1?-C¿8? carbonyle, ainsi que leurs sels, hydrates, solvates et isomères optiques physiologiquement acceptables, leur procédé de fabrication et médicaments renfermant ces composés, utilisés pour le traitement de maladies thromboemboliques.
Designated States: AU, BG, BR, CA, CN, CZ, FI, HU, JP, KR, KZ, NO, NZ, PL, RO, RU, SI, SK, UA, US.
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE).
Publication Language: German (DE)
Filing Language: German (DE)