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Machine translation
1. (WO1994027603) ALKALINE AND ACID PHOSPHATASE INHIBITORS IN TREATMENT OF NEUROLOGICAL DISORDERS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1994/027603    International Application No.:    PCT/US1994/006186
Publication Date: 08.12.1994 International Filing Date: 01.06.1994
Chapter 2 Demand Filed:    29.12.1994    
IPC:
A61K 31/00 (2006.01), A61K 31/19 (2006.01), A61K 31/305 (2006.01), A61K 31/425 (2006.01), A61K 33/00 (2006.01), A61K 33/16 (2006.01)
Applicants: CORTEX PHARMACEUTICALS, INC. [US/US]; 15241 Barranca Parkway, Irvine, CA 92718 (US)
Inventors: KELLEHER, Judith, A.; (US).
EVELETH, David, D., Jr.; (US)
Agent: KRUSE, Norman, J.; Townsend and Townsend Khourie and Crew, Steuart Street Tower, One Market Plaza, San Francisco, CA 94105-1492 (US)
Priority Data:
08/071,281 01.06.1993 US
Title (EN) ALKALINE AND ACID PHOSPHATASE INHIBITORS IN TREATMENT OF NEUROLOGICAL DISORDERS
(FR) INHIBITEURS DE PHOSPHATASE ALCALINE ET ACIDE UTILISES DANS LE TRAITEMENT DE TROUBLES NEUROLOGIQUES
Abstract: front page image
(EN)The present invention provides a method of inhibiting $g(b)-amyloid toxicity in brain cells. The method includes administering to the cells an amount of an alkaline phosphatase inhibitor which is pharmacologically effective to reduce degeneration in the cells. Methods of treatment of peripheral neuropathy are also provided using acid or alkaline phosphatase inhibitors.
(FR)L'invention se rapporte à un procédé pour inhiber la toxicité de la $g(b)-amyloïde dans les cellules du cerveau. Ce procédé consiste à administrer à ces cellules un agent inhibiteur de la phosphatase alcaline selon une quantité qui est efficace d'un point de vue pharmacologique pour réduire la dégénération dans ces cellules. L'invention décrit également des procédés pour traiter les neuropathies périphériques en utilisant des inhibiteurs de la phosphatase acide ou alcaline.
Designated States: AT, AU, BB, BG, BR, BY, CA, CH, CN, CZ, DE, DK, ES, FI, GB, GE, HU, JP, KG, KP, KR, KZ, LK, LU, LV, MD, MG, MN, MW, NL, NO, NZ, PL, PT, RO, RU, SD, SE, SI, SK, TJ, TT, UA, UZ, VN.
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)