WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO1994026275) 2-PYRIDYLMETHYLENEPOLYAZAMACROCYCLOPHOSPHONIC ACIDS, COMPLEXES AND DERIVATIVES THEREOF, FOR USE AS CONTRAST AGENTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1994/026275    International Application No.:    PCT/US1994/005009
Publication Date: 24.11.1994 International Filing Date: 05.05.1994
Chapter 2 Demand Filed:    02.12.1994    
IPC:
A61K 51/04 (2006.01), C07D 401/06 (2006.01), C07F 9/6524 (2006.01), C07F 9/6558 (2006.01), G01R 33/28 (2006.01)
Applicants: THE DOW CHEMICAL COMPANY [US/US]; 2030 Dow Center, Abbott Road, Midland, MI 48640 (US)
Inventors: KIEFER, Garry, E.; (US).
KIM, Won, D.; (US)
Agent: KIMBLE, Karen, L.; The Dow Chemical Company, Patent Department, P.O. Box 1967, Midland, MI 48641-01967 (US)
Priority Data:
057,588 06.05.1993 US
Title (EN) 2-PYRIDYLMETHYLENEPOLYAZAMACROCYCLOPHOSPHONIC ACIDS, COMPLEXES AND DERIVATIVES THEREOF, FOR USE AS CONTRAST AGENTS
(FR) ACIDES 2-PYRIDYLMETHYLENEPOLYAZAMACROCYCLOPHOSPHONIQUES, COMPLEXES ET DERIVES DE CES ACIDES, UTILISABLES COMME AGENTS DE CONTRASTE
Abstract: front page image
(EN)2-Pyridylmethylenepolyazamacrocyclophosphonic acid compounds and their derivatives are disclosed which may form inert complexes with Gd, Mn or Fe ions. The overall charge of the complex can be varied to alter the $i(in vivo) biolocalization. The complexes are useful as contrast agents for diagnostic purposes.
(FR)L'invention se rapporte à des composés à base d'acides 2-pyridylméthylènepolyazamacrocyclophosphoniques et à leurs dérivés, qui peuvent former des complexes inertes avec des ions Gd, Mn ou Fe. La charge globale du complexe peut être amenée à varier pour modifier la biolocalisation $i(in vivo). Ces complexes sont utiles comme agents de contraste dans des techniques de diagnostique.
Designated States: AT, AU, BB, BG, BR, BY, CA, CH, CN, CZ, DE, DK, ES, FI, GB, HU, JP, KR, KZ, LK, LU, LV, MG, MN, MW, NL, NO, NZ, PL, PT, RO, RU, SD, SE, SI, SK, UA, UZ, VN.
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)