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1. (WO1994025566) 1-N-ETHYL GENTAMICIN DERIVATIVES, AND THE METHOD FOR PREPARING THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1994/025566    International Application No.:    PCT/CN1994/000029
Publication Date: 10.11.1994 International Filing Date: 23.04.1994
Chapter 2 Demand Filed:    21.11.1994    
IPC:
C12P 19/28 (2006.01)
Applicants: JIANGSU INSTITUTE OF MICROBIOLOGY [CN/CN]; 121 Qianrong Road, Wuxi Jiangsu Province 214063 (CN) (For All Designated States Except US).
ZHAO, Min [CN/CN]; (CN) (For US Only).
FAN, Jin [CN/CN]; (CN) (For US Only).
LIU, Jun [CN/CN]; (CN) (For US Only).
HU, Xiaoling [CN/CN]; (CN) (For US Only).
FAN, Mingqi [CN/CN]; (CN) (For US Only)
Inventors: ZHAO, Min; (CN).
FAN, Jin; (CN).
LIU, Jun; (CN).
HU, Xiaoling; (CN).
FAN, Mingqi; (CN)
Agent: SHANGHAI PATENT AND TRADEMARK AGENCY; 435 Guiping Lu, Shanghai 200233 (CN)
Priority Data:
93112412.3 23.04.1993 CN
Title (EN) 1-N-ETHYL GENTAMICIN DERIVATIVES, AND THE METHOD FOR PREPARING THEREOF
(FR) DERIVES DE 1-N-ETHYL GENTAMICIME ET LEUR PROCEDE DE PREPARATION
Abstract: front page image
(EN)The present invention relates to the field of microorganisms and antibiotics. In particular, it relates to a new mutant strain and the method for mutagenizing breeding thereof, and the use of the new strain to produce a single ingredient gentamicin C¿1?a, and then using it as a useful intermediate (parent nuclear) for semisynthesizing 1-N-ethyl gentamicin derivatives, and to a composition which consists of semisynthesized 1-N-ethyl gentamicin derivatives as active ingredient and pharmacologically acceptable additives, and the method for preparing thereof.
(FR)Cette invention concerne les domaines des microorganismes et des antibiotiques. Il s'agit plus particulièrement d'une nouvelle souche mutante et d'un procédé de mutagénèse de sa descendance, de l'utilisation de la nouvelle souche pour produire de la gentamicine C¿1?a mono ingrédient, de l'utilisation de cette dernière comme intermédiaire utile (parent nucléaire) pour semi-synthétiser des dérivés de 1-N-éthyl gentamicine, d'une composition constituée de dérivés semi-synthétisés de 1-N-éthyl gentamicine comme ingrédient actif et d'additifs pharmacologiquement acceptables, et de son procédé de préparation.
Designated States: AT, AU, BB, BG, BR, BY, CA, CH, CN, CZ, DE, DK, ES, FI, GB, HU, JP, KP, KR, KZ, LK, LU, LV, MG, MN, MW, NL, NO, NZ, PL, PT, RO, RU, SD, SE, SK, UA, US, UZ, VN.
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)