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Machine translation
1. (WO1994015928) PIPERAZINE DERIVATIVES AS 5-HT ANTAGONISTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1994/015928    International Application No.:    PCT/GB1993/002661
Publication Date: 21.07.1994 International Filing Date: 24.12.1993
Chapter 2 Demand Filed:    18.07.1994    
IPC:
C07D 213/36 (2006.01), C07D 217/22 (2006.01), C07D 239/42 (2006.01), C07D 295/096 (2006.01)
Applicants: JOHN WYETH & BROTHER LIMITED [GB/GB]; Huntercombe Lane South, Taplow, Maidenhead, Berkshire SL6 0PH (GB) (For All Designated States Except US).
WARD, Terence, James [GB/GB]; (GB) (For US Only).
ASHWELL, Mark, Antony [GB/GB]; (GB) (For US Only)
Inventors: WARD, Terence, James; (GB).
ASHWELL, Mark, Antony; (GB)
Agent: BROWN, Keith, John, Symons; Wyeth Laboratories, Huntercombe Lane South, Taplow, Maidenhead, Berkshire SL6 0PH (GB)
Priority Data:
9300194.9 06.01.1993 GB
Title (EN) PIPERAZINE DERIVATIVES AS 5-HT ANTAGONISTS
(FR) DERIVES DE PIPERAZINE UTILISES COMME ANTAGONISTES DE 5-HT
Abstract: front page image
(EN)Piperazine derivatives of formula (I) and their pharmaceutically acceptable salts are 5-HT¿1A? binding agents and may be used, for example, as anxiolytics. In the formula, R and R?3¿ are hydrogen or lower alkyl or R?3¿ is spirocycloalkyl, R?1¿ and R?2¿ are aryl or heteroaryl radicals and n is 1 or 2 and m is 1 to 3 and the total of n + m is 2 - 4.
(FR)Des dérivés de pipérazine de formule (I) et leurs sels pharmaceutiquement acceptables constituent des agents de liaison aux 5-HT¿1A? et peuvent être utilisés, par exemple, comme agents anxiolytiques. Dans la formule, R et R?3¿ représentent hydrogène ou alkyle inférieur, ou bien R?3¿ représente spirocycloalkyle, R?1¿ et R?2¿ représentent des radicaux aryle ou héteroaryle, n vaut 1 ou 2 et m est compris entre 1 et 3, et le total de n + m est compris entre 2 et 4.
Designated States: AU, BB, BG, BR, BY, CA, CZ, FI, HU, JP, KP, KR, KZ, LK, MG, MN, MW, NO, NZ, PL, RO, RU, SD, SK, UA, US, VN.
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)