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Machine translation
1. (WO1994001392) (-)-RITODRINE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1994/001392    International Application No.:    PCT/JP1993/000896
Publication Date: 20.01.1994 International Filing Date: 30.06.1993
IPC:
A61K 31/135 (2006.01), C07C 215/60 (2006.01)
Applicants: MEIJI SEIKA KABUSHIKI KAISHA [JP/JP]; 4-16, Kyobashi 2-chome, Chuo-ku, Tokyo 104 (JP) (For All Designated States Except US).
YAMAZAKI, Naoki [JP/JP]; (JP) (For US Only).
FUKUDA, Yoshimasa [JP/JP]; (JP) (For US Only).
SHIBAZAKI, Yoshiaki [JP/JP]; (JP) (For US Only).
NIIZATO, Tetsutarou [JP/JP]; (JP) (For US Only).
KOSUGI, Isao [JP/JP]; (JP) (For US Only).
YOSHIOKA, Shin [JP/JP]; (JP) (For US Only)
Inventors: YAMAZAKI, Naoki; (JP).
FUKUDA, Yoshimasa; (JP).
SHIBAZAKI, Yoshiaki; (JP).
NIIZATO, Tetsutarou; (JP).
KOSUGI, Isao; (JP).
YOSHIOKA, Shin; (JP)
Agent: SATO, Kazuo; Kyowa Patent & Law Office, Room 323, Fuji Bldg., 2-3, Marunouchi 3-chome, Chiyoda-ku, Tokyo 100 (JP)
Priority Data:
4/174087 01.07.1992 JP
4/210482 06.08.1992 JP
Title (EN) (-)-RITODRINE
(FR) (-)-RITODRINE
Abstract: front page image
(EN)(-)-Ritodrine, i.e. (-)-erythro-1-(p-hydroxyphenyl)-2-[2-(p-hydroxyphenyl)ethylamino]-1-propanol, which is substantially free from the (+)-isomer, or a salt thereof. This compound has a potent effect of inhibiting uterine contraction as compared with (±)-ritodrine and (+)-ritodrine and a toxicity comparable to those of the other ritodrines, and hence is usable as a highly safe remedy for threatened premature birth and abortion and a remedy for dysmenorrhea.
(FR)(-)-ritodrine, c'est-à-dire le (-)-érythro-1-(p-hydroxyphényl)-2-[2-(p-hydroxyphényl)éthylamino]-1-propanol, sensiblement exempt du (+)-isomère, ou d'un sel de celui-ci. Ce composé présente un effet d'inhibition de la contraction utérine plus puissant que celui de la (±)-ritodrine et de la (+)-ritodrine, ainsi qu'une toxicité comparable à celle des autres ritodrines. Il est donc utilisable comme remède très sûr en cas de risque d'une naissance avant-terme ou d'un avortement, et comme remède contre la dysménorrhée.
Designated States: CA, JP, KR, US.
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)