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Machine translation
1. (WO1994000568) HIV-SENSITIVE TRANSGENIC RABBIT, USE THEREOF AS AN ANIMAL MODEL, AND METHOD FOR OBTAINING SAME
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1994/000568    International Application No.:    PCT/FR1993/000598
Publication Date: 06.01.1994 International Filing Date: 17.06.1993
Chapter 2 Demand Filed:    19.01.1994    
IPC:
C07K 14/775 (2006.01), C12N 15/85 (2006.01)
Applicants: TRANSGENE S.A. [FR/FR]; 11, rue de Molsheim, F-67000 Strasbourg (FR) (For All Designated States Except US).
MEHTALI, Majid [FR/FR]; (FR) (For US Only).
PAVIRANI, Andréa [IT/FR]; (FR) (For US Only)
Inventors: MEHTALI, Majid; (FR).
PAVIRANI, Andréa; (FR)
Agent: WARCOIN, Jacques; Cabinet Regimbeau, 26, avenue Kléber, F-75116 Paris (FR)
Priority Data:
92/07466 19.06.1992 FR
Title (EN) HIV-SENSITIVE TRANSGENIC RABBIT, USE THEREOF AS AN ANIMAL MODEL, AND METHOD FOR OBTAINING SAME
(FR) LAPIN TRANSGENIQUE SENSIBLE AU HIV, SON USAGE A TITRE DE MODELE ANIMAL, ET SON PROCEDE D'OBTENTION
Abstract: front page image
(EN)An HIV-sensitive transgenic rabbit having inserted into the genome thereof an exogenous DNA fragment comprising at least one DNA sequence which codes for membrane marker CD4 of human T cells (hCD4), or an analogue thereof, and is controlled by elements capable of causing its expression. The use of this rabbit as an animal model, and a method for obtaining said rabbit, are also disclosed.
(FR)L'invention a pour objet un lapin transgénique sensible au HIV dans le génome duquel est inséré un fragment d'ADN exogène qui comporte au moins une séquence d'ADN codant pour le marqueur membranaire CD4 des lymphocytes T humains (hCD4) ou un analogue de celui-ci, placée sous le contrôle d'éléments capables d'assurer son expression; ainsi que son usage à titre de modèle-animal et son procédé d'obtention.
Designated States: CA, JP, US.
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE).
Publication Language: French (FR)
Filing Language: French (FR)