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1. (WO1993020046) INDAN-1,3-DIONE AND INDAN-1,2,3-TRIONE DERIVATIVES, PROCESSES FOR PREPARATION OF SAME AND THEIR USE AS THERAPEUTIC AGENTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1993/020046    International Application No.:    PCT/FR1993/000329
Publication Date: 14.10.1993 International Filing Date: 01.04.1993
IPC:
C07C 45/27 (2006.01), C07C 45/28 (2006.01), C07C 45/63 (2006.01), C07C 45/67 (2006.01), C07C 49/733 (2006.01), C07C 49/755 (2006.01), C07C 233/32 (2006.01), C07C 243/28 (2006.01), C07C 243/38 (2006.01), C07C 251/68 (2006.01), C07C 251/84 (2006.01), C07C 281/02 (2006.01), C07C 281/06 (2006.01), C07C 281/12 (2006.01), C07C 311/49 (2006.01), C07C 317/34 (2006.01), C07C 337/08 (2006.01), C07D 207/34 (2006.01), C07D 209/12 (2006.01), C07D 213/86 (2006.01), C07D 213/87 (2006.01), C07D 213/88 (2006.01), C07D 241/24 (2006.01), C07D 295/135 (2006.01), C07D 307/68 (2006.01), C07D 317/66 (2006.01), C07D 333/38 (2006.01), C07D 401/04 (2006.01), C07D 409/04 (2006.01)
Applicants: INNOTHERA [FR/FR]; 10, avenue Paul-Vaillant-Couturier, F-94110 Arcueil (FR) (JP only).
CUGNON DE SEVRICOURT, Michel [FR/FR]; (FR) (For US Only).
DAQUET, Catherine [FR/FR]; (FR) (For US Only).
FINET, Michel [FR/FR]; (FR) (For US Only).
LE MARQUER, Florence [FR/FR]; (FR) (For US Only).
ROBBA, Max [FR/FR]; (FR) (For US Only).
TEMBO, Norbert, Olivier [FR/FR]; (FR) (For US Only).
YANNIC-ARNOULT, Sylvie [FR/FR]; (FR) (For US Only).
TORREGROSA, Jean-Luc [FR/FR]; (FR) (For US Only)
Inventors: CUGNON DE SEVRICOURT, Michel; (FR).
DAQUET, Catherine; (FR).
FINET, Michel; (FR).
LE MARQUER, Florence; (FR).
ROBBA, Max; (FR).
TEMBO, Norbert, Olivier; (FR).
YANNIC-ARNOULT, Sylvie; (FR).
TORREGROSA, Jean-Luc; (FR)
Agent: CABINET MALEMONT; 42, avenue du Président-Wilson, F-75116 Paris (FR)
Priority Data:
92/04071 03.04.1992 FR
Title (EN) INDAN-1,3-DIONE AND INDAN-1,2,3-TRIONE DERIVATIVES, PROCESSES FOR PREPARATION OF SAME AND THEIR USE AS THERAPEUTIC AGENTS
(FR) DERIVES D'INDANE-1,3-DIONE ET D'INDANE-1,2,3-TRIONE, LEURS PROCEDES DE PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
Abstract: front page image
(EN)Compounds of formula (I) used as therapeutic agents in which R¿2? and R¿3? are independently H, C¿1?-C¿4? alkoxy or OH and (A, B) = (oxygen, oxygen) in which case either R or R¿1? is OH, halogen, secondary amino or tertiary amine while the other denotes NHCOR¿4?, NHNHCOR¿5? or NHNHCOCONH¿2? or R and R¿1? together form =N-NH-CO-R'¿5?, =N-NH-CO-CO-NH¿2?, =N-NH-R¿6?, =N-R¿7?, =N-O-CO-R¿8? or =C(CH3)-NH-NH-CO-R¿9?; or (A,B) = (N-NH-CX-NHR¿10?, oxygen) in which case R and R¿1? together form =N-OH.
(FR)Composés utiles en thérapeutique de formule (I) dans laquelle R¿2? et R¿3? représentent indépendamment l'un de l'autre H, alkoxy en C¿1?-C¿4? ou OH et (A, B) = (oxygène, oxygène), auquel cas l'un parmi R et R¿1? représente OH, halogène, amino secondaire ou amine tertiaire et l'autre représente NHCOR¿4?, NHNHCOR¿5? ou NHNHCOCONH¿2? ou bien R et R¿1? forment ensemble =N-NH-CO-R'¿5?, =N-NH-CO-CO-NH¿2?, =N-NH-R¿6?, =N-R¿7?, =N-O-CO-R¿8? ou =C(CH¿3?)-NH-NH-CO-R¿9?; ou (A, B) = (N-NH-CX-NHR¿10?, oxygène), auquel cas R et R¿1? forment ensemble =N-OH.
Designated States: JP, US.
Publication Language: French (FR)
Filing Language: French (FR)