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Machine translation
1. (WO1993019786) HIGH AFFINITY, STRONGLY NEUTRALIZING MONOCLONAL ANTIBODIES AGAINST THE CD-4 BINDING SITE OF GP120 OF HUMAN IMMUNODEFICIENCY VIRUS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1993/019786    International Application No.:    PCT/US1993/003010
Publication Date: 14.10.1993 International Filing Date: 31.03.1993
Chapter 2 Demand Filed:    27.10.1993    
IPC:
A61K 38/00 (2006.01), C07K 16/10 (2006.01)
Applicants: THE PUBLIC HEALTH RESEARCH INSTITUTE OF THE CITY OF NEW YORK, INC. [US/US]; 455 First Avenue, New York, NY 10016 (US) (For All Designated States Except US).
TILLEY, Shermaine [US/US]; (US) (For US Only).
PINTER, Abraham [US/US]; (US) (For US Only)
Inventors: TILLEY, Shermaine; (US).
PINTER, Abraham; (US)
Agent: JACOBS, Seth, H.; Davis Hoxie Faithfull & Hapgood, 45 Rockefeller Plaza, New York, NY 10111 (US)
Priority Data:
07/861,108 31.03.1992 US
Title (EN) HIGH AFFINITY, STRONGLY NEUTRALIZING MONOCLONAL ANTIBODIES AGAINST THE CD-4 BINDING SITE OF GP120 OF HUMAN IMMUNODEFICIENCY VIRUS
(FR) ANTICORPS MONOCLONAUX FORTEMENT NEUTRALISANTS ET POSSEDANT UNE AFFINITE IMPORTANTE, DIRIGES CONTRE LE SITE DE LIAISON CD-4 DE LA GLYCOPROTEINE GP120 DU VIRUS IMMUNODEFICITAIRE HUMAIN
Abstract: front page image
(EN)mAbs are described which have high affinity for, and strongly neutralize, HIV-1. The mAbs are specific for an epitope that is partially or completely within the CD-4 binding site of gp120.
(FR)Anticorps monoclonaux présentant une affinité pour le VIH-1 et neutralisant fortement ce dernier. Ces anticorps monoclonaux sont spécifiques contre un déterminant antigénique (épitope) qui est situé partiellement ou entièrement dans le site de liaison CD-4 de la glycoprotéine gp120.
Designated States: AU, JP, US.
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE).
Publication Language: English (EN)
Filing Language: English (EN)