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1. WO1993004205 - MONOCLONAL ANTIBODIES TO PUTATIVE HCV E2/NS1 PROTEINS AND METHODS FOR USING SAME

Publication Number WO/1993/004205
Publication Date 04.03.1993
International Application No. PCT/US1992/007189
International Filing Date 21.08.1992
Chapter 2 Demand Filed 22.03.1993
IPC
C07K 14/18 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005from viruses
08RNA viruses
18Togaviridae, e.g. flavivirus, pestivirus, yellow fever virus, hepatitis C virus, japanese encephalitis virus
C07K 16/10 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
08against material from viruses
10from RNA viruses
CPC
C07K 14/005
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005from viruses
C07K 16/109
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
08against material from viruses
10from RNA viruses ; , e.g. hepatitis E virus
1081Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus
109Hepatitis C virus; Hepatitis G virus
C07K 2317/34
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
2317Immunoglobulins specific features
30characterized by aspects of specificity or valency
34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
C12N 2770/24222
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2770ssRNA Viruses positive-sense
00011ssRNA Viruses positive-sense
24011Flaviviridae
24211Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
24222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
G01N 33/5767
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
576for hepatitis
5767non-A, non-B hepatitis
Y10S 436/82
YSECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
10TECHNICAL SUBJECTS COVERED BY FORMER USPC
STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
436Chemistry: analytical and immunological testing
82Hepatitis associated antigens and antibodies
Applicants
  • ABBOTT LABORATORIES [US]/[US]
Inventors
  • MEHTA, Smriti, U.
  • JOHNSON, Jill, E.
  • DAILEY, Stephen, H.
  • DESAI, Suresh, M.
  • DEVARE, Sushil, G.
Agents
  • GORMAN, Edward, Hoover, Jr.
  • POREMBSKI, Priscilla, E.
Priority Data
748,29221.08.1991US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) MONOCLONAL ANTIBODIES TO PUTATIVE HCV E2/NS1 PROTEINS AND METHODS FOR USING SAME
(FR) ANTICORPS MONOCLONAUX CONTRE LES PROTEINES E2/NS1 D'HCV PUTATIVES ET PROCEDES D'UTILISATION DE CES ANTICORPS
Abstract
(EN)
Monoclonal antibodies which specifically bind to Hepatitis C Virus (HCV) E2/NS1 antigen. Also provided are hybridoma cell lines which secrete these monoclonal antibodies, methods for using these monoclonal antibodies, and assay kits for assays which contain these monoclonal antibodies.
(FR)
L'invention se rapporte à des anticorps monoclonaux qui se lient spécifiquement à l'antigène E2/NS1 du virus de l'hépatite C (HCV). L'invention décrit également des lignées de cellules hybridomes qui sécrètent ces anticorps monoclonaux, des procédés d'utilisation de ces anticorps monoclonaux et des kits pour des analyses qui contiennent ces anticorps monoclonaux.
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