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1. WO1993003766 - MULTIPLE ANTIGEN PEPTIDES FOR USE AS HIV VACCINES

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Publication Number WO/1993/003766
Publication Date 04.03.1993
International Application No. PCT/US1992/006688
International Filing Date 11.08.1992
Chapter 2 Demand Filed 09.02.1993
IPC
A61K 39/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
C07K 14/16 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005from viruses
08RNA viruses
15Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus, human T-cell leukaemia-lymphoma virus
155Lentiviridae, e.g. human immunodeficiency virus (HIV), visna-maedi virus, equine infectious anaemia virus
16HIV-1
CPC
A61K 39/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
C07K 14/005
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005from viruses
C07K 2319/40
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
2319Fusion polypeptide
40containing a tag for immunodetection, or an epitope for immunisation
C07K 2319/735
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
2319Fusion polypeptide
70containing domain for protein-protein interaction
735containing a domain for self-assembly, e.g. a viral coat protein (includes phage display)
C12N 2740/16122
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2740Reverse Transcribing RNA Viruses
00011Reverse Transcribing RNA Viruses
10011Retroviridae
16011Human Immunodeficiency Virus, HIV
16111concerning HIV env
16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Applicants
  • REPLIGEN CORPORATION [US]/[US]
  • THE ROCKEFELLER UNIVERSITY [US]/[US]
Inventors
  • TAM, James, P.
  • PROFY, Albert, T.
Agents
  • CLARK, Paul, T.
Priority Data
744,28113.08.1991US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) MULTIPLE ANTIGEN PEPTIDES FOR USE AS HIV VACCINES
(FR) PEPTIDES ANTIGENIQUES MULTIPLES DESTINES A ETRE UTILISES COMME VACCINS CONTRE LE VIH
Abstract
(EN)
In general, the invention features a multiple antigenic peptide system including a dentritic core and a peptide, wherein the peptide includes the sequence IGPGR (SEQ ID NO: 3), and the multiple antigen peptide system, when injected into a mammal, is capable of eliciting an immune response.
(FR)
L'invention présente en général un système de peptides antigéniques multiples comprenant un noyau dendritique et un peptide, ce dernier comprenant la séquence IGPGR (SEQ ID NO:3). Lorsqu'on l'injecte dans un mammifère, ce système de peptides antigéniques est à même de provoquer une réponse immunitaire.
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