WO1993003170 A FERMENTATION PROCESS FOR PRODUCING NATAMYCIN

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Publication Number WO/1993/003170

Publication Date 18.02.1993

International Application No. PCT/US1992/006323

International Filing Date 05.08.1992

Chapter 2 Demand Filed 22.02.1993

IPC

CPC

Applicants

BIO-TECHNICAL RESOURCES [US]/[US]

Inventors

EISENSCHINK, Michael, Allen
MILLIS, James, R.
OLSON, Phillip, Terry

Agents

STEVENSON, Robert, B.

Priority Data

740,545

05.08.1991

Publication Language English (en)

Filing Language English (EN)

Designated States

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Title

(EN) A FERMENTATION PROCESS FOR PRODUCING NATAMYCIN

(FR) PROCEDE DE FERMENTATION POUR LA PRODUCTION DE NATAMYCINE

Abstract

(EN) A natamycin producing Streptomyces species ferments to produce natamycin. A spore suspension of the Streptomyces species is propagated in a predetermined medium to obtain a quantity of Streptomyces cells. The Streptomyces cells ferment in a predetermined production medium to produce a recoverable amount of natamycin.

(FR) L'invention concerne un procédé de fermentation d'une espèce de $i(Streptomyces) afin de produire de la natamicyne. Une suspension de spores de l'espèce de $i(Streptomyces) se propage dans un milieu prédéterminé afin d'obtenir une quantité de cellules de $i(Streptomyces). Les cellules de $i(Streptomyces) fermentent dans un milieu de production prédéterminé afin de produire une quantité récupérable de natamycine.

C	CHEMISTRY; METALLURGY
12	BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P	FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
19	Preparation of compounds containing saccharide radicals
44	Preparation of O-glycosides, e.g. glucosides
60	having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
62	the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin

C	CHEMISTRY; METALLURGY
12	BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P	FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
19	Preparation of compounds containing saccharide radicals
44	Preparation of O-glycosides, e.g. glucosides
60	having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
62	the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin

C	CHEMISTRY; METALLURGY
12	BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P	FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
19	Preparation of compounds containing saccharide radicals
44	Preparation of O-glycosides, e.g. glucosides
60	having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
62	the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
626	Natamycin; Pimaricin; Tennecetin

C	CHEMISTRY; METALLURGY
12	BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P	FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
19	Preparation of compounds containing saccharide radicals
44	Preparation of O-glycosides, e.g. glucosides
60	having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
62	the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
626	Natamycin; Pimaricin; Tennecetin

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1. WO1993003170 - A FERMENTATION PROCESS FOR PRODUCING NATAMYCIN