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1. WO1993002210 - APPARATUS AND METHODS FOR PRESERVING, TRANSPORTING, STORING, RE-HYDRATING AND DELIVERING VIABLE MICROORGANISMS

Publication Number WO/1993/002210
Publication Date 04.02.1993
International Application No. PCT/US1992/006135
International Filing Date 21.07.1992
Chapter 2 Demand Filed 01.02.1993
IPC
C12M 1/24 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
24tube or bottle type
C12N 1/04 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
1Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
04Preserving or maintaining viable microorganisms
E21B 47/00 2012.1
EFIXED CONSTRUCTIONS
21EARTH OR ROCK DRILLING; MINING
BEARTH OR ROCK DRILLING; OBTAINING OIL, GAS, WATER, SOLUBLE OR MELTABLE MATERIALS OR A SLURRY OF MINERALS FROM WELLS
47Survey of boreholes or wells
F04B 47/02 2006.1
FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
04POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
BPOSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
47Pumps or pumping installations specially adapted for raising fluids from great depths, e.g. well pumps
02the driving mechanisms being situated at ground level
F04B 49/06 2006.1
FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
04POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
BPOSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
49Control of, or safety measures for, machines, pumps, or pumping installations, not otherwise provided for in, or of interest apart from, groups F04B1/-F04B47/196
06Control using electricity
CPC
C12M 45/03
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
45Means for pre-treatment of biological substances
03by control of the humidity or content of liquids; Drying
C12M 45/22
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
45Means for pre-treatment of biological substances
22Means for packing or storing viable microorganisms
C12N 1/04
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
1Microorganisms, e.g. protozoa; Compositions thereof
04Preserving or maintaining viable microorganisms
E21B 47/007
EFIXED CONSTRUCTIONS
21EARTH DRILLING; MINING
BEARTH DRILLING, e.g. DEEP DRILLING
47Survey of boreholes or wells
007Measuring stresses in a pipe string or casing
E21B 47/009
EFIXED CONSTRUCTIONS
21EARTH DRILLING; MINING
BEARTH DRILLING, e.g. DEEP DRILLING
47Survey of boreholes or wells
008Monitoring of down-hole pump systems, e.g. for the detection of "pumped-off" conditions
009Monitoring of walking-beam pump systems
F04B 47/02
FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
04POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
BPOSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
47Pumps or pumping installations specially adapted for raising fluids from great depths, e.g. well pumps
02the driving mechanisms being situated at ground level
Applicants
  • CHRISOPE TECHNOLOGIES, INC. [US]/[US]
Inventors
  • CHRISOPE, Gerald, L.
  • ROBERTS, Nell, C.
Agents
  • BROOKHART, Walter, R.
Priority Data
733,69622.07.1991US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) APPARATUS AND METHODS FOR PRESERVING, TRANSPORTING, STORING, RE-HYDRATING AND DELIVERING VIABLE MICROORGANISMS
(FR) DISPOSITIF ET PROCEDES DE CONSERVATION, TRANSPORT, STOCKAGE, REHYDRATATION ET ADMINISTRATION DE MICRO-ORGANISMES VIABLES
Abstract
(EN) The present invention is directed to systems and methods for preserving, transporting, storing, re-hydrating and delivering viable microorganisms. More particularly, the present invention is directed to a kit and method for preserving and storing dried, microbiological organisms for re-hydrating and delivering specific and reproducible numbers of viable organisms therefrom. The kit and method of the present invention provides the capability to deliver a known quantity of rehydrated microorganisms as a single, total dose of cells without the inaccuracies and safety hazards associated with standard needle, syringe or pipette transfer systems. The kit includes first and second vial and cap combinations, the first (10) carrying the dried organisms (40) in a dry, biologically inert atmosphere and the second carrying a pre-measured quantity of re-hydrating fluid (140). A quantitative number of selected microbiological organisms are dried under mild conditions, i.e., ambient temperature and pressure using forced air to flow, to fixative sites on the underside of the first cap (20) engaged in sealing relation with the first vial (10). Transfer of that cap to the second vial containing the re-hydrating fluid provides easy re-hydration and the ability to deliver specific and reproducible numbers of viable organisms after extended storage periods at normal refrigeration temperatures.
(FR) La présente invention se rapporte à des systèmes et des procédés de conservation, transport, stockage, réhydratation et administration de micro-organismes viables. L'invention se rapporte plus particulièrement à un coffret et à un procédé de conservation et de stockage d'organismes microbiologiques séchés consistant à réhydrater et administrer des quantités reproductibles et spécifiques de ces microorganismes viables. Le coffret et le procédé de la présente invention offrent la possibilité d'administrer une quantité connue de micro-organismes réhydratés sous forme d'une dose unique, complète de cellules, sans les imprécisions et les risques liés aux systèmes classiques à aiguille, à seringue ou de transfert par pipette. Le coffret comprend un premier et un second flacon et une combinaison de bouchons, le premier (10) contenant les organismes séchés (40) dans une atmosphère sèche, biologiquement inerte, et le second contenant une quantité prémesurée de fluide réhydratant (140). Une quantité définie d'organismes microbiologiques sélectionnés est séchée à des conditions modérées, par ex., à une température et une pression ambiantes utilisant de l'air pulsé pour s'écouler, vers des sites fixatifs sur la partie inférieure du premier bouchon (20) engagé hermétiquement dans le premier flacon (10). Le transfert de ce bouchon vers le second flacon contenant le fluide réhydratant permet une réhydratation facile et une capacité à administrer des quantités reproductibles et spécifiques d'organismes viables après un certain temps de stockage à des températures de réfrigération normales.
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