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1. WO1993002203 - FR901451 SUBSTANCE, PROCESS FOR PREPARATION THEREOF AND USE THEREOF

Publication Number WO/1993/002203
Publication Date 04.02.1993
International Application No. PCT/JP1992/000894
International Filing Date 14.07.1992
Chapter 2 Demand Filed 01.02.1993
IPC
A61K 35/74 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
66Microorganisms or materials therefrom
74Bacteria
C12P 1/04 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
1Preparation of compounds or compositions, not provided for in groups C12P3/-C12P39/121; General processes for the preparation of compounds or compositions by using microorganisms or enzymes
04by using bacteria
CPC
A61K 31/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
A61P 29/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29Non-central analgesic, antipyretic or anti-inflammatory agents, e.g antirheumatic agents; Non-steroidal anti-inflammatory drugs (NSAIDs)
A61P 37/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37Drugs for immunological or allergic disorders
A61P 43/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
C07G 17/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
GCOMPOUNDS OF UNKNOWN CONSTITUTION
17Other compounds of unknown constitution
C12N 1/205
Applicants
  • FUJISAWA PHARMACEUTICAL CO., LTD. [JP]/[JP] (AllExceptUS)
  • HATANAKA, Hiroshi [JP]/[JP] (UsOnly)
  • TAKASE, Shigehiro [JP]/[JP] (UsOnly)
  • FUJITA, Takashi [JP]/[JP] (UsOnly)
  • OKAMOTO, Masanori [JP]/[JP] (UsOnly)
  • OKUHARA, Masakuni [JP]/[JP] (UsOnly)
Inventors
  • HATANAKA, Hiroshi
  • TAKASE, Shigehiro
  • FUJITA, Takashi
  • OKAMOTO, Masanori
  • OKUHARA, Masakuni
Agents
  • SEKI, Hideo
Priority Data
9115811.322.07.1991GB
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) FR901451 SUBSTANCE, PROCESS FOR PREPARATION THEREOF AND USE THEREOF
(FR) SUBSTANCE FR901451, PROCEDE DE PREPARATION ET UTILISATION DE CETTE SUBSTANCE
Abstract
(EN) A new FR901451 substance which is produced by culturing an FR901451 substance-producing strain of the genus $i(Flexibacter) in a nutrient medium, this new substance possessing a human leukocyte elastase-inhibiting activity.
(FR) L'invention se rapporte à une nouvelle substance FR901451, qu'on produit en cultivant une souche, productrice de cette substance FR901451, du genre $i(Flexibacter) dans un milieu nutritif, cette nouvelle substance possédant des propriétés d'inhibition de la leucocyte élastase humaine.
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