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1. WO1992016528 - NEW BI- AND TRICYCLIC AMINOALCOHOL ESTERS, THEIR PREPARATION AND THEIR USE IN MEDICAMENTS

Publication Number WO/1992/016528
Publication Date 01.10.1992
International Application No. PCT/EP1992/000489
International Filing Date 05.03.1992
Chapter 2 Demand Filed 08.10.1992
IPC
C07D 451/10 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
451Heterocyclic compounds containing 8-azabicyclo octane, 9-azabicyclo nonane, or 3-oxa-9-azatricyclo nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
02containing not further condensed 8-azabicyclo octane or 3-oxa-9-azatricyclo nonane ring systems, e.g. tropane; Cyclic acetals thereof
04with hetero atoms directly attached in position 3 of the 8-azabicyclo octane or in position 7 of the 3-oxa-9-azatricyclo nonane ring system
06Oxygen atoms
10acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
C07D 451/14 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
451Heterocyclic compounds containing 8-azabicyclo octane, 9-azabicyclo nonane, or 3-oxa-9-azatricyclo nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
14containing 9-azabicyclo nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof
C07D 471/20 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
471Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/-C07D463/251
12in which the condensed system contains three hetero rings
20Spiro-condensed systems
CPC
A61P 11/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
A61P 25/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
02for peripheral neuropathies
C07D 451/10
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
451Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
02containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
04with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
06Oxygen atoms
10acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
C07D 451/14
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
451Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
14containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof
Applicants
  • BOEHRINGER INGELHEIM KG [DE]/[DE] (AT, BE, CH, CS, DE, DK, ES, FI, FR, GB, GR, HU, IT, JP, KR, LU, MC, NL, NO, PL, SE)
  • BOEHRINGER INGELHEIM INTERNATIONAL GMBH [DE]/[DE] (AU, CA, GB)
  • BANHOLZER, Rolf [DE]/[DE] (UsOnly)
  • BAUER, Rudolf [DE]/[DE] (UsOnly)
  • REICHL, Richard [DE]/[DE] (UsOnly)
Inventors
  • BANHOLZER, Rolf
  • BAUER, Rudolf
  • REICHL, Richard
Common Representative
  • BOEHRINGER INGELHEIM KG
Priority Data
P 41 08 393.815.03.1991DE
Publication Language German (DE)
Filing Language German (DE)
Designated States
Title
(DE) NEUE ESTER BI- UND TRICYCLISCHER AMINOALKOHOLE, IHRE HERSTELLUNG UND IHRE VERWENDUNG IN ARZNEIMITTELN
(EN) NEW BI- AND TRICYCLIC AMINOALCOHOL ESTERS, THEIR PREPARATION AND THEIR USE IN MEDICAMENTS
(FR) ESTERS NOUVEAUX D'AMINO-ALCOOLS BICYCLIQUES ET TRICYCLIQUES, LEUR PREPARATION ET LEUR UTILISATION DANS DES MEDICAMENTS
Abstract
(DE)
Die neuen Verbindungen der Formel (I): A-O-CO-Z (die Bedeutung von A und Z ist in der Beschreibung erläutert) können nach üblichen Methoden hergestellt werden; sie eignen sich als Wirkstoffe für anticholinergener Arzneimittel.
(EN)
New compounds having the formula (I): A-O-CO-Z, in which A and Z have the meanings given in the description, may be prepared by conventional processes; they are useful as active substances in medicaments.
(FR)
De nouveaux composés répondant à la formule (I): A-O-CO-Z, dans laquelle A et Z ont la signification donnée dans la description, peuvent être préparés selon des méthodes classiques; ils sont utiles comme substances actives dans des médicaments.
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