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1. (WO1992011846) PARTICULATES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1992/011846    International Application No.:    PCT/EP1992/000021
Publication Date: 23.07.1992 International Filing Date: 04.01.1992
Chapter 2 Demand Filed:    10.07.1992    
A61K 9/51 (2006.01), A61K 47/48 (2006.01), A61K 49/18 (2006.01), C12Q 1/48 (2006.01), C12Q 1/68 (2006.01), C12Q 1/70 (2006.01)
Applicants: ST GEORGE'S ENTERPRISES LIMITED [GB/GB]; St George's Hospital Medical School, Cranner Terrace, Tooting, London SW17 0RE (GB) (For All Designated States Except US).
FILLER, Aaron, Gershon [US/GB]; (GB) (For US Only).
LEVER, Andrew, Michael, Lindsay [GB/GB]; (GB) (For US Only)
Inventors: FILLER, Aaron, Gershon; (GB).
LEVER, Andrew, Michael, Lindsay; (GB)
Agent: COCKBAIN, Julian, R., M.; Frank B Dehn & Co., Imperial House, 15-19 Kingsway, London WC2B 6UZ (GB)
Priority Data:
9100233.7 07.01.1991 GB
9100981.1 16.01.1991 GB
9102146.9 31.01.1991 GB
9110876.1 20.05.1991 GB
9116373.3 30.07.1991 GB
9117851.7 19.08.1991 GB
9118676.7 30.08.1991 GB
9119665.9 13.09.1991 GB
Abstract: front page image
(EN)There is provided a means of cellular level therapy or prophylaxis whereby endocytosable particles are administered so as to emit cytotoxic radiation or to release metal cations having a therapeutic or prophylactic effect, eg. a viral replication suppressing effect, within cells such as macrophages following their uptake by these cells.
(FR)Thérapie ou prophylaxie au niveau des cellules, comprenant l'administration de particules aptes à subir une endocytase afin qu'elles émettent un rayonnement cytotoxique ou qu'elles dégagent des cations métalliques présentant un effet thérapeutique ou prophylactique tel qu'un effet de suppression de la réplication virale, à l'intérieur de cellules telles que les macrophages et après leur absorption par ces cellules.
Designated States: AU, CA, JP, NO, US.
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, MC, NL, SE).
Publication Language: English (EN)
Filing Language: English (EN)